Antibacterial and antifungal terpenes from the medicinal angiosperms of Asia and the Pacific: Haystacks and gold needles
C Wiart, G Kathirvalu, CS Raju, V Nissapatorn… - Molecules, 2023 - mdpi.com
This review identifies terpenes isolated from the medicinal Angiosperms of Asia and the
Pacific with antibacterial and/or antifungal activities and analyses their distribution …
Pacific with antibacterial and/or antifungal activities and analyses their distribution …
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
[HTML][HTML] Artemisia annua and Artemisia afra extracts exhibit strong bactericidal activity against Mycobacterium tuberculosis
MC Martini, T Zhang, JT Williams… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Emergence of drug-resistant and multidrug-resistant
Mycobacterium tuberculosis (Mtb) strains is a major barrier to tuberculosis (TB) eradication …
Mycobacterium tuberculosis (Mtb) strains is a major barrier to tuberculosis (TB) eradication …
[HTML][HTML] Molecular insights into artemisinin resistance in Plasmodium falciparum: An updated review
WA Azmi, AFM Rizki, Y Djuardi, IM Artika… - Infection, Genetics and …, 2023 - Elsevier
Malaria still poses a major burden on human health around the world, especially in endemic
areas. Plasmodium resistance to several antimalarial drugs has been one of the major …
areas. Plasmodium resistance to several antimalarial drugs has been one of the major …
Efficacy and mechanism of actions of natural antimicrobial drugs
L Ye, J Zhang, W Xiao, S Liu - Pharmacology & Therapeutics, 2020 - Elsevier
Microbial infections have significantly increased over the last decades, and the mortality
rates remain unacceptably high. The emergence of new resistance patterns and the spread …
rates remain unacceptably high. The emergence of new resistance patterns and the spread …
Artemisinin as a therapeutic vs. its more complex Artemisia source material
PJ Weathers - Natural Product Reports, 2023 - pubs.rsc.org
Covering: up to 2017–2022 Many small molecule drugs are first discovered in nature,
commonly the result of long ethnopharmacological use by people, and then characterized …
commonly the result of long ethnopharmacological use by people, and then characterized …
Natural products and their analogues acting against Mycobacterium tuberculosis: A recent update
G Kumar - Drug Development Research, 2023 - Wiley Online Library
Tuberculosis (TB) remains one of the deadliest infectious diseases caused by
Mycobacterium tuberculosis (M. tb). It is responsible for significant causes of mortality and …
Mycobacterium tuberculosis (M. tb). It is responsible for significant causes of mortality and …
Heme-based gas sensors in nature and their chemical and biotechnological applications
ACS Gondim, WG Guimarães, EHS Sousa - BioChem, 2022 - mdpi.com
Sensing is an essential feature of life, where many systems have been developed. Diatomic
molecules such as O2, NO and CO exhibit an important role in life, which requires …
molecules such as O2, NO and CO exhibit an important role in life, which requires …
[HTML][HTML] Polycationic phosphorous dendrimer potentiates multiple antibiotics against drug-resistant mycobacterial pathogens
Mycobacterium tuberculosis (Mtb), causative agent of tuberculosis (TB) and non-tubercular
mycobacterial (NTM) pathogens such as Mycobacterium abscessus are one of the most …
mycobacterial (NTM) pathogens such as Mycobacterium abscessus are one of the most …
Loss of glycerol catabolism confers carbon-source-dependent artemisinin resistance in Mycobacterium tuberculosis
MC Martini, MN Alonso, JH Cafiero… - Antimicrobial Agents …, 2024 - journals.asm.org
In view of the urgent need for new antibiotics to treat human infections caused by multidrug-
resistant pathogens, drug repurposing is gaining strength due to the relatively low research …
resistant pathogens, drug repurposing is gaining strength due to the relatively low research …