Objective To develop a new evidence‐based, pharmacologic treatment guideline for
rheumatoid arthritis (RA). Methods We conducted systematic reviews to synthesize the …

Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for …

Abstract Objective The 1987 American College of Rheumatology (ACR; formerly, the
American Rheumatism Association) classification criteria for rheumatoid arthritis (RA) have …

The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

Objective Autoantibodies have been demonstrated in single serum samples from healthy
subjects up to 10 years before they developed rheumatoid arthritis (RA). However, the time …

Handgrip strength (HGS) is associated with several chronic diseases, cognitive decline,
length of hospital-stay, and mortality. More importantly, HGS is one of the diagnostic criteria …

Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

Objective To determine the efficacy and safety of treatment with rituximab plus methotrexate
(MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response to …

Objective To compare the incidence of cardiovascular (CV) events in persons with
rheumatoid arthritis (RA) with that in people from the general population, adjusting for …

Background and Purpose: One use of clinical measures is the prediction of future outcomes.
The purpose of this systematic review was to summarize the literature addressing the value …