The wide spectrum of cryoglobulinemic vasculitis and an overview of therapeutic advancements

F Dammacco, G Lauletta, A Vacca - Clinical and Experimental Medicine, 2023 - Springer
Immunoglobulins that reversibly precipitate at temperatures below 37° C are called
cryoglobulins (CGs). Cryoglobulinemia often manifests as cryoglobulinemic vasculitis (CV) …

New frontiers in precision medicine for Sjogren's syndrome

L Chatzis, PG Vlachoyiannopoulos… - Expert review of …, 2021 - Taylor & Francis
Introduction: Sjögren's syndrome is a unique systemic autoimmune disease, placed in the
center of systemic autoimmunity and at the crossroads of autoimmunity and …

Clinical picture, outcome and predictive factors of lymphoma in primary Sjögren's syndrome: results from a harmonized dataset (1981–2021)

LG Chatzis, IE Stergiou, AV Goules, V Pezoulas… - …, 2022 - academic.oup.com
Abstract Objectives Primary Sjögren's Syndrome (pSS) carries the highest risk for non-
Hodgkin's lymphoma (NHL) development among systemic autoimmune diseases. However …

Regulation of MMP9 transcription by ETS1 in immortalized salivary gland epithelial cells of patients with salivary hypofunction and primary Sjögren's syndrome

B Noll, FB Mougeot, MT Brennan, JLC Mougeot - Scientific Reports, 2022 - nature.com
Primary Sjögren's syndrome (pSS) patients exhibit enhanced degradation of the salivary
epithelium initially through MMP9 overexpression. We assessed the expression of MMP9 …

Renal involvement in Sjőgren's syndrome: Predictors and impact on patient outcomes

R Chatterjee, A Balakrishnan, R Kharbanda… - Rheumatology …, 2023 - Springer
Renal disease in primary Sjogren's Syndrome (pSS) occurs as tubulointerstitial nephritis
(TIN) or glomerulonephritis (GN). Data from India on pSS are sparse and even less on …

Manifestations and management of Sjögren's disease

M Maleki-Fischbach, L Kastsianok, M Koslow… - Arthritis Research & …, 2024 - Springer
Sjögren's disease is a heterogeneous autoimmune disorder that may be associated with
systemic manifestations such as pulmonary or articular involvement. Systemic complications …

Isolated anti-Ro52 identifies a severe subset of Sjögren's syndrome patients

AYS Lee, T Putty, MW Lin, S Swaminathan… - Frontiers in …, 2023 - frontiersin.org
Introduction Serum autoantibodies targeting the SSA/Ro proteins are a key component of
the classification criteria for the diagnosis of Sjögren's syndrome (SS). Most patients' serum …

Recent updates in the diagnosis and management of cryoglobulinemic vasculitis

E Treppo, L Quartuccio, S De Vita - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Cryoglobulinemic vasculitis (CV), also known as mixed cryoglobulinemic
syndrome (MCS), is a systemic vasculitis that affects small blood vessels. It exhibits a wide …

Cryoglobulinemia in systemic lupus erythematosus: a retrospective study of 213 patients

Y Roubertou, S Mainbourg, A Hot, D Fouque… - Arthritis Research & …, 2022 - Springer
Objectives The clinical value of cryoglobulinemia (CG) in systemic lupus erythematosus
(SLE) is largely unknown. The aim of this retrospective study was to describe the …

Phases and Natural History of Sjögren's Disease: A New Model for an Old Disease?

AYS Lee, JJ Wang, TP Gordon… - Arthritis Care & …, 2023 - Wiley Online Library
Sjögren's disease (SjD) is an archetypal and heterogenous autoimmune disorder that is
characterized by exocrine glandular dysfunction. A proportion of patients develop severe …