Microfluidic nanoparticles for drug delivery

Y Liu, G Yang, Y Hui, S Ranaweera, CX Zhao - Small, 2022 - Wiley Online Library
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …

Current advances in multifunctional nanocarriers based on marine polysaccharides for colon delivery of food polyphenols

S Tie, M Tan - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Inflammatory bowel disease (IBD) has been considered as a chronic disease that is difficult
to cure and needs lifelong treatment. Marine polysaccharides with good biocompatibility and …

Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

A review of microfluidic experimental designs for nanoparticle synthesis

AG Niculescu, DE Mihaiescu… - International Journal of …, 2022 - mdpi.com
Microfluidics is defined as emerging science and technology based on precisely
manipulating fluids through miniaturized devices with micro-scale channels and chambers …

One-Pot Microfluidics to Engineer Chitosan Nanoparticles Conjugated with Antimicrobial Peptides Using “Photoclick” Chemistry: Validation Using the Gastric …

DR Fonseca, PM Alves, E Neto… - … Applied Materials & …, 2024 - ACS Publications
Surface bioconjugation of antimicrobial peptides (AMP) onto nanoparticles (AMP-NP) is a
complex, multistep, and time-consuming task. Herein, a microfluidic system for the one-pot …

Chitosan and its derivatives as polymeric anti-viral therapeutics and potential anti-SARS-CoV-2 nanomedicine

RSL Tan, P Hassandarvish, CF Chee, LW Chan… - Carbohydrate …, 2022 - Elsevier
The coronavirus pandemic, COVID-19 has a global impact on the lives and livelihoods of
people. It is characterized by a widespread infection by the severe acute respiratory …

Microfluidic synthesis of nanomaterials for biomedical applications

Y Huang, C Liu, Q Feng, J Sun - Nanoscale Horizons, 2023 - pubs.rsc.org
The field of nanomaterials has progressed dramatically over the past decades with important
contributions to the biomedical area. The physicochemical properties of nanomaterials, such …

Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies

RM Aman, RA Zaghloul, MS El-Dahhan - Scientific reports, 2021 - nature.com
Allantoin (ALL) is a phytochemical possessing an impressive array of biological activities.
Nonetheless, developing a nanostructured delivery system targeted to augment the gastric …

A herringbone mixer based microfluidic device HBEXO-chip for purifying tumor-derived exosomes and establishing miRNA signature in pancreatic cancer

Y Zhang, X Tong, L Yang, R Yin, Y Li, D Zeng… - Sensors and Actuators B …, 2021 - Elsevier
Exosomes, which are lipid membrane-enclosed nanovesicles (30− 150 nm in diameter),
contain abundant proteomic and genetic information. Specifically, tumor-derived exosomes …

CD44-targeted carriers: the role of molecular weight of hyaluronic acid in the uptake of hyaluronic acid-based nanoparticles

E Chiesa, A Greco, F Riva, R Dorati, B Conti… - Pharmaceuticals, 2022 - mdpi.com
Nanotechnology offers advanced biomedical tools for diagnosis and drug delivery, stressing
the value of investigating the mechanisms by which nanocarriers interact with the biological …