Early detection and assessment of invisible cracks in compressed oral solid dosage forms

T Sultan, VS Dave, C Cetinkaya - International Journal of Pharmaceutics, 2023 - Elsevier
In the pharmaceutical manufacturing industry, real-time in situ quality monitoring for
detecting defects at an early stage is a desirable ability, especially in high-rate production, to …

Micro-viscoelastic characterization of compressed oral solid dosage forms with ultrasonic wave dispersion analysis

T Sultan, S Paul, EH Rozin, YC Tseng… - AAPS …, 2022 - Springer
Due to their constituent powders, the materials of advanced compressed oral solid dosage
(OSD) forms are micro-composites and strongly visco-elastic at macro-and micro-length …

Machine learning modeling for ultrasonic quality attribute assessment of pharmaceutical tablets for continuous manufacturing and real-time release testing

T Sultan, EH Rozin, S Paul, YC Tseng, VS Dave… - International Journal of …, 2024 - Elsevier
In in-process quality monitoring for Continuous Manufacturing (CM) and Critical Quality
Attributes (CQA) assessment for Real-time Release (RTR) testing, ultrasonic …

Machine learning framework for extracting micro-viscoelastic and micro-structural properties of compressed oral solid dosage forms

T Sultan, EH Rozin, S Paul, YC Tseng… - International Journal of …, 2023 - Elsevier
A compressed pharmaceutical oral solid dosage (OSD) form is a strongly micro-viscoelastic
material composite arranged as a network of agglomerated particles due to its constituent …

Non-destructive detection of disintegrant levels in compressed oral solid dosage forms

T Sultan, EH Rozin, VS Dave, C Cetinkaya - International Journal of …, 2023 - Elsevier
Quality issues related to compressed oral solid dosage (OSD) forms, such as tablets, arise
during the design, development, and production stages, despite established processes and …

Monitoring for the effects of extruder nozzle temperature on the micro-mechanical properties of 3D printed phononic artifacts

MS Sutopa, T Sultan, EH Rozin, X Xu, J Gardan… - Journal of Manufacturing …, 2023 - Elsevier
Investigating the impact of process parameters on the mechanical properties of the printed
parts is essential for optimizing 3D Printing/Additive Manufacturing (3DP/AM) processes to …

ИЗУЧЕНИЕ ВОЗМОЖНОСТИ ИСПОЛЬЗОВАНИЯ ПРЯМОГО ПРЕССОВАНИЯ ДЛЯ ПОЛУЧЕНИЯ ТАБЛЕТОК ЛАПАТИНИБА

ОЛ ОРЛОВА, МВ ДМИТРИЕВА, ЗС ШПРАХ… - ЕСТЕСТВЕННЫЕ И … - elibrary.ru
Лапатиниб одобрен Министерством здравоохранения РФ в качестве препарата 1
линии терапии наиболее агрессивной формы рака молочной железы (РМЖ) …