Lipid metabolism in cancer: New perspectives and emerging mechanisms
LA Broadfield, AA Pane, A Talebi, JV Swinnen… - Developmental cell, 2021 - cell.com
Tumors undergo metabolic transformations to sustain uncontrolled proliferation, avoid cell
death, and seed in secondary organs. An increased focus on cancer lipid metabolism has …
death, and seed in secondary organs. An increased focus on cancer lipid metabolism has …
Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire
Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …
molecules and are also involved in numerous critical biological processes. Studies …
Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver …
Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …
physiological processes including signal transduction, cellular metabolism and tissue …
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging
Numerous studies have shown that epigenetic age—an individual's degree of aging based
on patterns of DNA methylation—can be computed and is associated with an array of factors …
on patterns of DNA methylation—can be computed and is associated with an array of factors …
Fatty acid requirements in ontogeny of marine and freshwater fish
DR Tocher - Aquaculture research, 2010 - Wiley Online Library
Essential fatty acid (EFA) requirements vary qualitatively and quantitatively with both species
and during ontogeny of fish, with early developmental stages and broodstock being critical …
and during ontogeny of fish, with early developmental stages and broodstock being critical …
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
H Guillou, D Zadravec, PGP Martin… - Progress in lipid research, 2010 - Elsevier
In mammalian cells, elongases and desaturases play critical roles in regulating the length
and degree of unsaturation of fatty acids and thereby their functions and metabolic fates. In …
and degree of unsaturation of fatty acids and thereby their functions and metabolic fates. In …
Methylation of ELOVL2 gene as a new epigenetic marker of age
P Garagnani, MG Bacalini, C Pirazzini, D Gori… - Aging cell, 2012 - Wiley Online Library
The discovery of biomarkers able to predict biological age of individuals is a crucial goal in
aging research. Recently, researchers' attention has turn toward epigenetic markers of …
aging research. Recently, researchers' attention has turn toward epigenetic markers of …
Fatty acid elongases in mammals: their regulation and roles in metabolism
A Jakobsson, R Westerberg, A Jacobsson - Progress in lipid research, 2006 - Elsevier
A significant amount of the fatty acids synthesized by the cytosolic enzyme complex fatty acid
synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids …
synthase (FAS) or taken up by the diet are further elongated into very long chain fatty acids …
[HTML][HTML] Is docosahexaenoic acid synthesis from α-linolenic acid sufficient to supply the adult brain?
AF Domenichiello, AP Kitson, RP Bazinet - Progress in lipid research, 2015 - Elsevier
Docosahexaenoic acid (DHA) is important for brain function, and can be obtained directly
from the diet or synthesized in the body from α-linolenic acid (ALA). Debate exists as to …
from the diet or synthesized in the body from α-linolenic acid (ALA). Debate exists as to …
Elongation of long-chain fatty acids.
AE Leonard, SL Pereira, H Sprecher, YS Huang - 2004 - cabidigitallibrary.org
Fatty acids are critical for the normal development and function of all organisms, and in
particular, very long chain PUFAs are necessary for the health and maintenance of higher …
particular, very long chain PUFAs are necessary for the health and maintenance of higher …