Structure of condensed phase peptides: insights from vibrational circular dichroism and Raman optical activity techniques
TA Keiderling - Chemical reviews, 2020 - ACS Publications
Peptides and proteins are naturally chiral molecular systems so that sensing their structure
and conformation with chirality-based spectral methods is an obvious and long-used …
and conformation with chirality-based spectral methods is an obvious and long-used …
Recent progress on the stereoselective synthesis of cyclic quaternary α-amino acids
C Cativiela, M Ordóñez - Tetrahedron: Asymmetry, 2009 - Elsevier
The most recent papers describing the stereoselective synthesis of cyclic quaternary α-
amino acids are collected in this review. The diverse synthetic approaches are classified …
amino acids are collected in this review. The diverse synthetic approaches are classified …
Helical screw‐sense preferences of peptides based on chiral, Cα‐tetrasubstituted α‐amino acids
M Crisma, C Toniolo - Peptide Science, 2015 - Wiley Online Library
The preferred helical screw senses of chiral α‐amino acids with a Cα‐tetrasubstituted α‐
carbon atom, as determined in the crystal state by X‐ray diffraction analyses on derivatives …
carbon atom, as determined in the crystal state by X‐ray diffraction analyses on derivatives …
Practical methods for the synthesis of symmetrically α, α-disubstituted α-amino acids
VA Soloshonok, AE Sorochinsky - Synthesis, 2010 - thieme-connect.com
This report provides an overview of the practical methods for preparing symmetrically α, α-
disubstituted α-amino acids and their derivatives. Despite the growing application of this …
disubstituted α-amino acids and their derivatives. Despite the growing application of this …
Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery—building chiral technology toolboxes
O Mcconnell, A Bach, C Balibar, N Byrne… - Chirality: the …, 2007 - Wiley Online Library
Abstract The application of Chiral Technology, or the (extensive) use of techniques or tools
for the determination of absolute stereochemistry and the enantiomeric or chiral separation …
for the determination of absolute stereochemistry and the enantiomeric or chiral separation …
Conformational analysis of chiral helical perfluoroalkyl chains by VCD
K Monde, N Miura, M Hashimoto… - Journal of the …, 2006 - ACS Publications
Conformational Analysis of Chiral Helical Perfluoroalkyl Chains by VCD | Journal of the
American Chemical Society ACS ACS Publications C&EN CAS Find my institution Log In Journal …
American Chemical Society ACS ACS Publications C&EN CAS Find my institution Log In Journal …
Enantio‐ and diastereoselective syntheses of cyclic Cα‐tetrasubstituted α‐amino acids and their use to induce stable conformations in short peptides
P Maity, B König - Peptide Science, 2008 - Wiley Online Library
Cα‐Tetrasubstituted α‐amino acids are widely used to design and prepare peptides and
peptide mimics with constrained conformations. Subcategories of these compounds are …
peptide mimics with constrained conformations. Subcategories of these compounds are …
Analysis of the Cartesian tensor transfer method for calculating vibrational spectra of polypeptides
NS Bieler, MP Haag, CR Jacob… - Journal of chemical …, 2011 - ACS Publications
The Cartesian Tensor Transfer Method (CTTM) was proposed as an efficient way to
calculate infrared, Raman, and Raman Optical Activity (ROA) spectra for large molecules …
calculate infrared, Raman, and Raman Optical Activity (ROA) spectra for large molecules …
One‐Handed Helical Screw Direction of Homopeptide Foldamer Exclusively Induced by Cyclic α‐Amino Acid Side‐Chain Chiral Centers
Y Demizu, M Doi, M Kurihara… - … A European Journal, 2012 - Wiley Online Library
Chiral cyclic α, α‐disubstituted amino acids,(3S, 4S)‐and (3R, 4R)‐1‐amino‐3, 4‐(dialkoxy)
cyclopentanecarboxylic acids ((S, S)‐and (R, R)‐Ac5cdOR; R: methyl, methoxymethyl), were …
cyclopentanecarboxylic acids ((S, S)‐and (R, R)‐Ac5cdOR; R: methyl, methoxymethyl), were …
Turn and helical peptide handedness governed exclusively by side-chain chiral centers
S Royo, WM De Borggraeve, C Peggion… - Journal of the …, 2005 - ACS Publications
We have examined the preferred 3D structure of homopeptides based on an α-amino acid
lacking the asymmetry at the α-carbon but exhibiting chirality in the side chains (at the two β …
lacking the asymmetry at the α-carbon but exhibiting chirality in the side chains (at the two β …