Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …

Transfection is a modern and powerful method used to insert foreign nucleic acids into
eukaryotic cells. The ability to modify host cells' genetic content enables the broad …

Gene therapy provides a promising approach in treating cancers with high efficacy and
selectivity and few adverse effects. Currently, the development of functional vectors with …

Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …

The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus
2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan …

Mesenchymal stem cells (MSCs) have been widely used in the fields of tissue engineering
and regenerative medicine due to their self-renewal capabilities and multipotential …

Transfection by means of non-viral gene delivery vectors is the cornerstone of modern gene
delivery. Despite the resources poured into the development of ever more effective …

Gene therapy promises to revolutionize biomedicine and personalized medicine by
modulating or compensating the expression of abnormal genes. The biggest obstacle for …