Programmable DNA cleavage using CRISPR–Cas9 enables efficient, site-specific genome
engineering in single cells and whole organisms. In the research arena, versatile CRISPR …

The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

TALEN were the first easy-to-use genome editing technology and sparked the genome
editing revolution. Their application in multiple species brought targeted mutagenesis to the …

Reproductive technology revolutionized dairy production during the past century. Artificial
insemination was first successfully applied to cattle in the early 1900s. The next major …

Genomic selection has revolutionized dairy cattle breeding. Since 2000, assays have been
developed to genotype large numbers of single-nucleotide polymorphisms (SNPs) at …

Treating livestock as senseless production machines has led to rampant depletion of natural
resources, enhanced greenhouse gas emissions, gross animal welfare violations, and other …

The CRISPR-Cas genome editing tools have been adopted rapidly in the research
community, and they are quickly finding applications in the commercial sector as well. Lest …

Selective breeding has been practiced since domestication, but early breeders commonly
selected on appearance (eg, coat color) rather than performance traits (eg, milk yield). A …

The human population is growing, and as a result we need to produce more food whilst
reducing the impact of farming on the environment. Selective breeding and genomic …

Ruminants are the only extant mammalian group possessing bony (osseous) headgear. We
obtained 221 transcriptomes from bovids and cervids and sequenced three genomes …