Structural basis for clearing of ribosome collisions by the RQT complex
K Best, K Ikeuchi, L Kater, D Best, J Musial… - Nature …, 2023 - nature.com
Translation of aberrant messenger RNAs can cause stalling of ribosomes resulting in
ribosomal collisions. Collided ribosomes are specifically recognized to initiate stress …
ribosomal collisions. Collided ribosomes are specifically recognized to initiate stress …
ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase
N babu Chinnam, R Thapar, AS Arvai… - Journal of Biological …, 2024 - ASBMB
Activating signal co-integrator complex 1 (ASCC1) acts with ASCC-ALKBH3 complex in
alkylation damage responses. ASCC1 uniquely combines two evolutionarily ancient …
alkylation damage responses. ASCC1 uniquely combines two evolutionarily ancient …
Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role
C Hu, Z Chen, G Wang, H Yang, J Ding - Structure, 2024 - cell.com
TRIP4 is a conserved transcriptional coactivator that is involved in the regulation of the
expression of multiple genes. It consists of a classical N-terminal C2HC5-like zinc-finger …
expression of multiple genes. It consists of a classical N-terminal C2HC5-like zinc-finger …
Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry
LM Welp, T Sachsenberg, A Wulf, A Chernev… - bioRxiv, 2024 - biorxiv.org
UV (ultra-violet) crosslinking with mass spectrometry (XL-MS) has been established for
identifying RNA-and DNA-binding proteins along with their domains and amino acids …
identifying RNA-and DNA-binding proteins along with their domains and amino acids …
Mechanistic investigation of eukaryotic quality control factors RQT and Mbf1
K Best - 2023 - edoc.ub.uni-muenchen.de
Translation is a central cellular process and thus tightly regulated by quality control
mechanisms. Monitoring the ribosome during translation is an elegant way to track the …
mechanisms. Monitoring the ribosome during translation is an elegant way to track the …