[HTML][HTML] Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

[HTML][HTML] Antibacterial gas therapy: strategies, advances, and prospects

TY Wang, XY Zhu, FG Wu - Bioactive Materials, 2023 - Elsevier
One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …

Photocontrol of antibacterial activity: shifting from UV to red light activation

M Wegener, MJ Hansen, AJM Driessen… - Journal of the …, 2017 - ACS Publications
The field of photopharmacology aims to introduce smart drugs that, through the
incorporation of molecular photoswitches, allow for the remote spatial and temporal control …

Carbon monoxide and its controlled release: therapeutic application, detection, and development of carbon monoxide releasing molecules (CORMs) miniperspective

K Ling, F Men, WC Wang, YQ Zhou… - Journal of Medicinal …, 2017 - ACS Publications
Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

[HTML][HTML] Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12

S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …

Harnessing transition metal scaffolds for targeted antibacterial therapy

C Weng, YLK Tan, WG Koh… - Angewandte Chemie …, 2023 - Wiley Online Library
Antimicrobial resistance, caused by persistent adaptation and growing resistance of
pathogenic bacteria to overprescribed antibiotics, poses one of the most serious and urgent …

Emerging delivery strategies of carbon monoxide for therapeutic applications: from CO gas to CO releasing nanomaterials

H Yan, J Du, S Zhu, G Nie, H Zhang, Z Gu, Y Zhao - Small, 2019 - Wiley Online Library
Carbon monoxide (CO) therapy has emerged as a hot topic under exploration in the field of
gas therapy as it shows the promise of treating various diseases. Due to the gaseous …

Role of carbon monoxide in host–gut microbiome communication

CP Hopper, LK De La Cruz, KV Lyles… - Chemical …, 2020 - ACS Publications
Nature is full of examples of symbiotic relationships. The critical symbiotic relation between
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …

[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3

HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …

Synergetic antimicrobial activity and mechanism of clotrimazole-linked CO-releasing molecules

SS Mendes, J Marques, E Mesterházy… - ACS bio & med …, 2022 - ACS Publications
Several metal-based carbon monoxide-releasing molecules (CORMs) are active CO donors
with established antibacterial activity. Among them, CORM conjugates with azole antibiotics …