[HTML][HTML] Chromatin remodelers: from function to dysfunction
G Längst, L Manelyte - Genes, 2015 - mdpi.com
Chromatin remodelers are key players in the regulation of chromatin accessibility and
nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent …
nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent …
Footprints of the sun: memory of UV and light stress in plants
R Müller-Xing, Q Xing, J Goodrich - Frontiers in plant science, 2014 - frontiersin.org
Sunlight provides the necessary energy for plant growth via photosynthesis but high light
and particular its integral ultraviolet (UV) part causes stress potentially leading to serious …
and particular its integral ultraviolet (UV) part causes stress potentially leading to serious …
Diversification of histone H2A variants during plant evolution
Among eukaryotes, the four core histones show an extremely high conservation of their
structure and form nucleosomes that compact, protect, and regulate access to genetic …
structure and form nucleosomes that compact, protect, and regulate access to genetic …
[HTML][HTML] The role of ISWI chromatin remodeling complexes in brain development and neurodevelopmental disorders
LR Goodwin, DJ Picketts - Molecular and Cellular Neuroscience, 2018 - Elsevier
Abstract The mammalian ISWI (Imitation Switch) genes SMARCA1 and SMARCA5 encode
the ATP-dependent chromatin remodeling proteins SNF2L and SNF2H. The ISWI proteins …
the ATP-dependent chromatin remodeling proteins SNF2L and SNF2H. The ISWI proteins …
Epigenetic mechanisms underlying nervous system diseases
IA Qureshi, MF Mehler - Handbook of clinical neurology, 2018 - Elsevier
Epigenetic mechanisms act as control systems for modulating genomic structure and activity
in response to evolving profiles of cell-extrinsic, cell-cell, and cell-intrinsic signals. These …
in response to evolving profiles of cell-extrinsic, cell-cell, and cell-intrinsic signals. These …
Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3. 3
Y Arimura, K Shirayama, N Horikoshi, R Fujita… - Scientific reports, 2014 - nature.com
The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular
aggressive cancer cells, where it can be mislocalized ectopically in the form of heterotypic …
aggressive cancer cells, where it can be mislocalized ectopically in the form of heterotypic …
The epigenetic tracks of aging
CI Weidner, W Wagner - Biological chemistry, 2014 - degruyter.com
Aging is associated with the deterioration of biological functions, which is either caused by
accumulation of random defects or mediated by a controlled process. This article provides …
accumulation of random defects or mediated by a controlled process. This article provides …
Spotlight on histone H2A variants: From B to X to Z
A Herchenröther, TM Wunderlich, J Lan… - Seminars in cell & …, 2023 - Elsevier
Chromatin, the functional organization of DNA with histone proteins in eukaryotic nuclei, is
the tightly-regulated template for several biological processes, such as transcription …
the tightly-regulated template for several biological processes, such as transcription …
Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis
ATM drives DNA repair by phosphorylating the histone variant H2AX. While ATM mutations
elicit prominent neurobehavioral phenotypes, neural roles for H2AX have been elusive. We …
elicit prominent neurobehavioral phenotypes, neural roles for H2AX have been elusive. We …
Structural and biochemical analyses of monoubiquitinated human histones H2B and H4
S Machida, S Sekine, Y Nishiyama… - Open …, 2016 - royalsocietypublishing.org
Monoubiquitination is a major histone post-translational modification. In humans, the histone
H2B K120 and histone H4 K31 residues are monoubiquitinated and may form …
H2B K120 and histone H4 K31 residues are monoubiquitinated and may form …