[HTML][HTML] Chromatin remodelers: from function to dysfunction

G Längst, L Manelyte - Genes, 2015 - mdpi.com
Chromatin remodelers are key players in the regulation of chromatin accessibility and
nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent …

Footprints of the sun: memory of UV and light stress in plants

R Müller-Xing, Q Xing, J Goodrich - Frontiers in plant science, 2014 - frontiersin.org
Sunlight provides the necessary energy for plant growth via photosynthesis but high light
and particular its integral ultraviolet (UV) part causes stress potentially leading to serious …

Diversification of histone H2A variants during plant evolution

T Kawashima, ZJ Lorković, R Nishihama, K Ishizaki… - Trends in plant …, 2015 - cell.com
Among eukaryotes, the four core histones show an extremely high conservation of their
structure and form nucleosomes that compact, protect, and regulate access to genetic …

[HTML][HTML] The role of ISWI chromatin remodeling complexes in brain development and neurodevelopmental disorders

LR Goodwin, DJ Picketts - Molecular and Cellular Neuroscience, 2018 - Elsevier
Abstract The mammalian ISWI (Imitation Switch) genes SMARCA1 and SMARCA5 encode
the ATP-dependent chromatin remodeling proteins SNF2L and SNF2H. The ISWI proteins …

Epigenetic mechanisms underlying nervous system diseases

IA Qureshi, MF Mehler - Handbook of clinical neurology, 2018 - Elsevier
Epigenetic mechanisms act as control systems for modulating genomic structure and activity
in response to evolving profiles of cell-extrinsic, cell-cell, and cell-intrinsic signals. These …

Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3. 3

Y Arimura, K Shirayama, N Horikoshi, R Fujita… - Scientific reports, 2014 - nature.com
The centromere-specific histone H3 variant, CENP-A, is overexpressed in particular
aggressive cancer cells, where it can be mislocalized ectopically in the form of heterotypic …

The epigenetic tracks of aging

CI Weidner, W Wagner - Biological chemistry, 2014 - degruyter.com
Aging is associated with the deterioration of biological functions, which is either caused by
accumulation of random defects or mediated by a controlled process. This article provides …

Spotlight on histone H2A variants: From B to X to Z

A Herchenröther, TM Wunderlich, J Lan… - Seminars in cell & …, 2023 - Elsevier
Chromatin, the functional organization of DNA with histone proteins in eukaryotic nuclei, is
the tightly-regulated template for several biological processes, such as transcription …

Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis

U Weyemi, BD Paul, AM Snowman, P Jailwala… - Nature …, 2018 - nature.com
ATM drives DNA repair by phosphorylating the histone variant H2AX. While ATM mutations
elicit prominent neurobehavioral phenotypes, neural roles for H2AX have been elusive. We …

Structural and biochemical analyses of monoubiquitinated human histones H2B and H4

S Machida, S Sekine, Y Nishiyama… - Open …, 2016 - royalsocietypublishing.org
Monoubiquitination is a major histone post-translational modification. In humans, the histone
H2B K120 and histone H4 K31 residues are monoubiquitinated and may form …