Nearly 130 years after the first insights into the existence of mitochondria, new
rolesassociated with these organelles continue to emerge. As essential hubs that dictate cell …

Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In
this Review we provide an integrated model for its pathogenesis. ARDS involves damage to …

The socio-economic, environmental, and health implications of diseases caused by
pathogenic microorganisms and their treatment using conventional antimicrobials are …

Nanosystem-mediated tumor radiosensitization strategy combining the features of X-ray with
infinite penetration depth and high atomic number elements shows considerable application …

Although glutamate is one of the most important excitatory neurotransmitters of the central
nervous system, its excessive extracellular concentration leads to uncontrolled continuous …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

In Diabetes, the chronic hyperglycemia and associated complications affecting peripheral
nerves are one of the most commonly occurring microvascular complications with an overall …

Peroxynitrite—the product of the diffusion-controlled reaction of nitric oxide with superoxide
radical—is a short-lived oxidant species that is a potent inducer of cell death. Conditions in …

Background Mitochondrial dysfunction and defects in oxidative metabolism are a
characteristic feature of many chronic illnesses not currently classified as mitochondrial …

cis-Diamminedichloroplatinum (II)(cisplatin) is an important chemotherapeutic agent useful
in the treatment of several cancers; however, it has several side effects such as …