Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics

AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Vagal pathways for microbiome-brain-gut axis communication

P Forsythe, J Bienenstock, WA Kunze - … : the microbiota-gut-brain axis in …, 2014 - Springer
There is now strong evidence from animal studies that gut microorganism can activate the
vagus nerve and that such activation plays a critical role in mediating effects on the brain …

[HTML][HTML] The forced swim test as a model of depressive-like behavior

R Yankelevitch-Yahav, M Franko… - Journal of visualized …, 2015 - pmc.ncbi.nlm.nih.gov
The goal of the present protocol is to describe the forced swim test (FST), which is one of the
most commonly used assays for the study of depressive-like behavior in rodents. The FST is …

The corticotropin-releasing factor family: physiology of the stress response

JM Deussing, A Chen - Physiological reviews, 2018 - journals.physiology.org
The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

Using the rat forced swim test to assess antidepressant-like activity in rodents

DA Slattery, JF Cryan - Nature protocols, 2012 - nature.com
The forced swim test (FST) is one of the most commonly used animal models for assessing
antidepressant-like behavior. This protocol details using the FST in rats, which takes place …

[HTML][HTML] The mouse forced swim test

A Can, DT Dao, M Arad, CE Terrillion… - Journal of …, 2012 - pmc.ncbi.nlm.nih.gov
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs,
antidepressant efficacy of new compounds, and experimental manipulations that are aimed …

A prefrontal cortex–brainstem neuronal projection that controls response to behavioural challenge

MR Warden, A Selimbeyoglu, JJ Mirzabekov, M Lo… - Nature, 2012 - nature.com
The prefrontal cortex (PFC) is thought to participate in high-level control of the generation of
behaviours (including the decision to execute actions); indeed, imaging and lesion studies …

Anxiety, depression, and decision making: a computational perspective

SJ Bishop, C Gagne - Annual review of neuroscience, 2018 - annualreviews.org
In everyday life, the outcomes of our actions are rarely certain. Further, we often lack the
information needed to precisely estimate the probability and value of potential outcomes as …

The forced swim test: Historical, conceptual and methodological considerations and its relationship with individual behavioral traits

A Armario - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The forced swim test (FST), developed by Porsolt and collaborators in 1977 to evaluate
antidepressant (AD) treatments in rodents, has become extensively used for this purpose …

Factors influencing behavior in the forced swim test

OV Bogdanova, S Kanekar, KE D'Anci… - Physiology & …, 2013 - Elsevier
The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …