The etiology of preeclampsia
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …
overlapping pathologic processes activate a common pathway consisting of endothelial cell …
[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders
S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
Preeclampsia: maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors
T Tomimatsu, K Mimura, S Matsuzaki, M Endo… - International journal of …, 2019 - mdpi.com
Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …
The competing risk approach for prediction of preeclampsia
D Wright, A Wright, KH Nicolaides - American journal of obstetrics and …, 2020 - Elsevier
The established method of the assessment of the risk for development of preeclampsia is to
identify risk factors from maternal demographic characteristics and medical history; in the …
identify risk factors from maternal demographic characteristics and medical history; in the …
Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity
Metformin is everywhere. Originally introduced in clinical practice as an antidiabetic agent,
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …
its role as a therapeutic agent is expanding to include treatment of prediabetes mellitus …
Early prediction of preeclampsia
LC Poon, KH Nicolaides - Obstetrics and gynecology …, 2014 - Wiley Online Library
Effective screening for the development of early onset preeclampsia (PE) can be provided in
the first‐trimester of pregnancy. Screening by a combination of maternal risk factors, uterine …
the first‐trimester of pregnancy. Screening by a combination of maternal risk factors, uterine …
[HTML][HTML] Implementation of the sFlt-1/PlGF ratio for prediction and diagnosis of pre-eclampsia in singleton pregnancy: implications for clinical practice
H Stepan, I Herraiz, D Schlembach… - … in Obstetrics & …, 2015 - ncbi.nlm.nih.gov
Pre-eclampsia (PE) is a leading cause of maternal and fetal/neonatal morbidity and mortality
worldwide. Clinical diagnosis and definition of PE is commonly based on the measurement …
worldwide. Clinical diagnosis and definition of PE is commonly based on the measurement …
Meta-analysis and systematic review to assess the role of soluble FMS-like tyrosine kinase-1 and placenta growth factor ratio in prediction of preeclampsia: the …
Preeclampsia is a major cause of morbidity and mortality worldwide. Numerous candidate
biomarkers have been proposed for diagnosis and prediction of preeclampsia …
biomarkers have been proposed for diagnosis and prediction of preeclampsia …
Plastics derived endocrine‐disrupting compounds and their effects on early development
Despite the fact that the estrogenic effects of bisphenols were first described 80 years ago,
recent data about its potential negative impact on birth outcome parameters raises a strong …
recent data about its potential negative impact on birth outcome parameters raises a strong …
Circulating angiogenic factor levels in hypertensive disorders of pregnancy
R Thadhani, E Lemoine, S Rana… - NEJM …, 2022 - evidence.nejm.org
Background Among women with hypertensive disorders of pregnancy, biomarkers may
stratify risk for developing preeclampsia with severe features (sPE). Methods Across 18 US …
stratify risk for developing preeclampsia with severe features (sPE). Methods Across 18 US …