[HTML][HTML] Infrared multiple photon dissociation (IRMPD) spectroscopy and its potential for the clinical laboratory

MJ Carlo, AL Patrick - Journal of Mass Spectrometry and Advances in the …, 2022 - Elsevier
Infrared multiple photon dissociation (IRMPD) spectroscopy is a powerful tool used to probe
the vibrational modes–and, by extension, the structure—of an ion within an ion trap mass …

[HTML][HTML] IRMPD spectroscopy and quantum-chemical simulations of the reaction products of cisplatin with the dipeptide CysGly

D Corinti, R Paciotti, C Coletti, N Re… - Journal of Inorganic …, 2023 - Elsevier
The inorganic antineoplastic drug cisplatin was made to react in solution with the dipeptide
cysteinylglycine (CysGly), chosen as a functional model of glutathione, and the reaction …

Elusive intermediates in cisplatin reaction with target amino acids: platinum (II)-cysteine complexes assayed by IR ion spectroscopy and DFT calculations

D Corinti, R Paciotti, C Coletti, N Re… - Journal of Inorganic …, 2022 - Elsevier
The reactivity of a widely used metal based antineoplastic drug, cisplatin, cis-PtCl 2 (NH 3)
2, with L-cysteine (Cys) has been investigated using a combination of electrospray …

Cation‐π Interactions between a Noble Metal and a Polyfunctional Aromatic Ligand: Ag+(benzylamine)

D Corinti, A Maccelli, B Chiavarino… - … A European Journal, 2022 - Wiley Online Library
The structure of an isolated Ag+ (benzylamine) complex is investigated by infrared multiple
photon dissociation (IRMPD) spectroscopy complemented with quantum chemical …

Structural Determination of Lysine-Linked Cisplatin Complexes via IRMPD Action Spectroscopy: NNs and NO Binding Modes of Lysine to Platinum Coexist

CC He, LA Hamlow, HA Roy… - The Journal of …, 2022 - ACS Publications
Despite its success as an anticancer drug, cisplatin suffers from resistance and produces
side effects. To overcome these limitations, amino-acid-linked cisplatin analogues have …

Ligation Motifs in Zinc-Bound Sulfonamide Drugs Assayed by IR Ion Spectroscopy

D Corinti, B Chiavarino, P Maitre, ME Crestoni… - Molecules, 2022 - mdpi.com
The sulfonamide–zinc ion interaction, performing a key role in various biological contexts, is
the focus of the present study, with the aim of elucidating ligation motifs in zinc complexes of …