The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening
conditions triggered by multiple intra-and extra-pulmonary injury factors, characterized by …

Context Ferulic acid (FA) has antioxidative and anti-inflammatory effects, and is a promising
drug to treat sepsis. Objective To study the therapeutic effect of FA in sepsis-induced acute …

Sepsis is a life-threatening organ dysfunction characterized by severe systemic inflammatory
response to infection. Effective treatment of bacterial sepsis remains a paramount clinical …

Background Sepsis is a life-threatening disease syndrome caused by a dysregulated host
response to infection and injury. Extracellular cold-inducible RNA-binding protein (eCIRP) …

Sepsis is one common cause of acute lung injury (ALI) and acute respiratory distress
syndrome (ARDS), which is closely associated with high mortality in intensive care units …

Isoliquiritin apioside (IA), a critical ingredient of Glycyrrhizae radix et rhizoma, has been
unveiled to possess remarkable pharmacological activity against oxidative stress and …

Acute lung injury (ALI) represents a frequent sepsis-induced inflammatory disorder.
Mesenchymal stromal cells (MSCs) elicit anti-inflammatory effects in sepsis. This study …

Ethnopharmacological relevance Yupingfengsan (YPFS) is a traditional Chinese medicine
decoction. YPFS comprises Astragalus mongholicus Bunge (Huangqi), Atractylodes rubra …

Background: Innate immune memory, also termed “trained immunity”, is thought to protect
against experimental models of infection, including sepsis. Trained immunity via …