Structural study for substrate recognition of human N‐terminal glutamine amidohydrolase 1 in the arginine N‐degron pathway

JM Kang, JS Park, JS Lee, JY Jang, BW Han - Protein Science, 2024 - Wiley Online Library
The N‐degron pathway determines the half‐life of proteins by selectively destabilizing the
proteins bearing N‐degrons. N‐terminal glutamine amidohydrolase 1 (NTAQ1) plays an …

PROTEOMIC APPROACHES TO IDENTIFY UNIQUE AND SHARED SUBSTRATES AMONG KINASE FAMILY MEMBERS

CL Howarth - 2023 - digitalcommons.dartmouth.edu
Protein phosphorylation is a reversible post-translational modification that is a critical
component of almost all signaling pathways. Kinases regulate substrate proteins through …

Pre-Clinical Research and Development of Novel FKBP12 Antagonists for Enhanced Wound Healing and Regenerative Therapy

BJ Peiffer - 2019 - jscholarship.library.jhu.edu
The combination of AMD3100 and low-dose FK506 has been shown to accelerate wound
healing in vivo. Though AMD3100 is known to work by releasing hematopoietic stem cells …