Efficacy and safety of intravitreal anti-VEGF therapy in diabetic retinopathy: what we have learned and what should we learn further?
Introduction Diabetic retinopathy (DR) is one of the most frequent microvascular
complications of diabetes that can lead to blindness. Laser treatment has been the gold …
complications of diabetes that can lead to blindness. Laser treatment has been the gold …
Cardiovascular adverse events with intravitreal anti–vascular endothelial growth factor drugs: a systematic review and meta-analysis of randomized clinical trials
NN Ntjam, M Thulliez, G Paintaud, F Salvo… - JAMA …, 2021 - jamanetwork.com
Importance Systemic safety of intravitreal anti-vascular endothelial growth factor (anti-VEGF)
is a matter of debate and regular updates are necessary. Objective To evaluate systemic …
is a matter of debate and regular updates are necessary. Objective To evaluate systemic …
[HTML][HTML] A real-world study of effectiveness of intravitreal bevacizumab and ranibizumab injection for treating retinal diseases in Thailand
S Kumluang, L Ingsrisawang, S Sangroongruangsri… - BMC …, 2019 - Springer
Background To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal
ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand …
ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand …
[HTML][HTML] Intravitreal vascular endothelial growth factor inhibitor use and renal function decline in patients with diabetic retinopathy
SH Ou, CH Yin, TL Chung, HY Chen, CL Chen… - International Journal of …, 2022 - mdpi.com
Adverse renal effects of systemic vascular endothelial growth factor (VEGF) inhibitor
treatment are well documented. We aimed to identify associations between intravitreal VEGF …
treatment are well documented. We aimed to identify associations between intravitreal VEGF …
[HTML][HTML] Bevacizumab for eye diseases–Legal, regulatory, and ethical overview
V Jose, S Radhakrishna, P Pipalava… - Indian journal of …, 2019 - journals.lww.com
Vascular endothelial growth factor (VEGF) inhibitors, ranibizumab, aflibercept, and
pegaptanib are approved treatments for certain eye diseases that occurs especially in the …
pegaptanib are approved treatments for certain eye diseases that occurs especially in the …
Cardiovascular risk in patients receiving ranibizumab for exudative age-related macular degeneration: a nationwide self-controlled case-series study
Aims To identify the association between ranibizumab and risk of stroke and acute
myocardial infarction (AMI) in patients with exudative age-related macular degeneration …
myocardial infarction (AMI) in patients with exudative age-related macular degeneration …
Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration: an update
C Costagliola, F Morescalchi, S Duse… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Intravitreal anti-VEGF is the most effective therapy for wet AMD, although
systemic effects on the endothelium cannot be excluded. Areas covered: The purpose of this …
systemic effects on the endothelium cannot be excluded. Areas covered: The purpose of this …
[HTML][HTML] The Association of Intravitreal Injections of Different Anti-Vascular Endothelial Growth Factor with Systemic Outcomes in Diabetic Patients
This retrospective cohort study aimed to assess the systemic effects of three commonly
available anti-vascular endothelial growth factor intravitreal injections in patients with …
available anti-vascular endothelial growth factor intravitreal injections in patients with …
Increased mortality after intravitreal injections of anti-VEGF for neovascular AMD among patients with prior stroke or acute myocardial infarction
YY Chen, YJ Lai, YF Yen, P Chou - Eye, 2022 - nature.com
Objectives To evaluate whether intravitreal injections (IVI) of anti-vascular endothelial
growth factor (anti-VEGF) in neovascular age-related macular degeneration (nAMD) patients …
growth factor (anti-VEGF) in neovascular age-related macular degeneration (nAMD) patients …
Real-world data and real-world evidence
X Sun - Advanced Statistics in Regulatory Critical Clinical …, 2022 - taylorfrancis.com
Real-World Data (RWD) is commonly defined as data collected in a non-randomized
controlled trial setting, highlighting the representativeness of RWD for an actual diagnosis …
controlled trial setting, highlighting the representativeness of RWD for an actual diagnosis …