Macrophage biology in the peripheral nervous system after injury
RE Zigmond, FD Echevarria - Progress in neurobiology, 2019 - Elsevier
Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …
From basics to clinical: a comprehensive review on spinal cord injury
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …
individuals each year. Over the past decades an enormous progress has been made in our …
Minocycline: far beyond an antibiotic
N Garrido‐Mesa, A Zarzuelo… - British journal of …, 2013 - Wiley Online Library
Minocycline is a second‐generation, semi‐synthetic tetracycline that has been in therapeutic
use for over 30 years because of its antibiotic properties against both gram‐positive and …
use for over 30 years because of its antibiotic properties against both gram‐positive and …
Spinal cord injury: pathophysiology, treatment strategies, associated challenges, and future implications
K Venkatesh, SK Ghosh, M Mullick… - Cell and tissue …, 2019 - Springer
Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …
Stroke and the immune system: from pathophysiology to new therapeutic strategies
R Macrez, C Ali, O Toutirais, B Le Mauff… - The Lancet …, 2011 - thelancet.com
Stroke is the second most common cause of death worldwide and a major cause of acquired
disability in adults. Despite tremendous progress in understanding the pathophysiology of …
disability in adults. Despite tremendous progress in understanding the pathophysiology of …
p38MAPK: stress responses from molecular mechanisms to therapeutics
LR Coulthard, DE White, DL Jones… - Trends in molecular …, 2009 - cell.com
The p38 MAPK protein kinases affect a variety of intracellular responses, with well-
recognized roles in inflammation, cell-cycle regulation, cell death, development …
recognized roles in inflammation, cell-cycle regulation, cell death, development …
[HTML][HTML] CDC Guidelines for the Prevention and Treatment of Anthrax, 2023
WA Bower - MMWR. Recommendations and Reports, 2023 - cdc.gov
This report updates previous CDC guidelines and recommendations on preferred
prevention and treatment regimens regarding naturally occurring anthrax. Also provided are …
prevention and treatment regimens regarding naturally occurring anthrax. Also provided are …
Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
BC Hains, SG Waxman - Journal of Neuroscience, 2006 - Soc Neuroscience
Traumatic spinal cord injury (SCI) results not only in motor impairment but also in chronic
central pain, which can be refractory to conventional treatment approaches. It has been …
central pain, which can be refractory to conventional treatment approaches. It has been …
Minocycline and neurodegenerative diseases
HS Kim, YH Suh - Behavioural brain research, 2009 - Elsevier
Minocycline is a semi-synthetic, second-generation tetracycline analog which is effectively
crossing the blood–brain barrier, effective against gram-positive and-negative infections. In …
crossing the blood–brain barrier, effective against gram-positive and-negative infections. In …
A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome
MJS Leigh, DV Nguyen, Y Mu, TI Winarni… - … of developmental & …, 2013 - journals.lww.com
Objective: Minocycline rescued synaptic abnormalities and improved behavior in the fragile
X mouse model. Previous open-label human studies demonstrated benefits in individuals …
X mouse model. Previous open-label human studies demonstrated benefits in individuals …