[HTML][HTML] HIV expression in infected T cell clones

JW Rausch, S Parvez, S Pathak, AA Capoferri… - Viruses, 2024 - mdpi.com
The principal barrier to an HIV-1 cure is the persistence of infected cells harboring
replication-competent proviruses despite antiretroviral therapy (ART). HIV-1 transcriptional …

[HTML][HTML] Targeting HIV persistence in the tissue

DKJ Pieren, A Benítez-Martínez… - Current Opinion in HIV …, 2024 - journals.lww.com
Targeting persistence in tissue reservoirs represents a complex but essential step towards
achieving HIV cure. Combinatorial strategies, particularly during the early phases of …

[HTML][HTML] Quantitative and Qualitative Distinctions between HIV-1 and SIV Reservoirs: Implications for HIV-1 Cure-Related Studies

JC Mudd - Viruses, 2024 - mdpi.com
The persistence of the latent viral reservoir is the main hurdle to curing HIV-1 infection. SIV
infection of non-human primates (NHPs), namely Indian-origin rhesus macaques, is the most …

[HTML][HTML] Phylogenetic position and genetic features of HIV-1 in CNS

MV Piterskiy, OA Khodakov, TV Mikheeva… - Journal of …, 2024 - microbiol.crie.ru
Background. Due to the wide coverage with antiretroviral therapy, the life expectancy of HIV
infected people has significantly increased. Against the background of a decrease in …

A simple phylogenetic approach to analyze hypermutated HIV proviruses reveals insights into their dynamics and persistence during antiretroviral therapy

A Shahid, BR Jones, MC Duncan, S MacLennan… - 2024 - researchsquare.com
Hypermutated proviruses, which arise in a single HIV replication cycle when host antiviral
APOBEC3 proteins introduce extensive G-to-A mutations throughout the viral genome …

[PDF][PDF] Филогенетическое положение и генетические особенности вируса иммунодефицита человека-1 в центральной нервной системе

МВ Питерский, ОА Ходаков, ТВ Михеева… - JOURNAL OF …, 2024 - researchgate.net
Аннотация Актуальность. Благодаря широкому охвату пациентов с ВИЧ-инфекцией
антиретровирусной терапией существенно увеличилась продолжительность жизни …

Phylogenetic methods for estimating human immunodeficiency virus 1 proviral integration dates

BR Jones - 2023 - open.library.ubc.ca
Human immunodeficiency virus 1 (HIV) maintains an ongoing pandemic. Despite combined
antiretroviral therapies (cART) that can suppress viral load, halt progression to acquired …