The emergence of multidrug resistance (MDR) pathogens and the rapid depletion of the
antibiotic arsenal have sparked interest in discovering and developing innovative …

Paracellular permeability across epithelial and endothelial cells is, in large part, regulated
by apical intercellular junctions also referred to as tight junctions (TJs). These junctions …

Fluorescence quenching is a common phenomenon of carbon quantum dots (CQDs) and
has been utilized to detect various compounds. Since CQDs are prepared by varied …

Nowadays, treating corneal diseases arising from injury to the corneal endothelium
necessitates donor tissue, but these corneas are extremely scarce. As a result, researchers …

Glaucoma presents a significant global health concern and affects millions of individuals
worldwide and predicted a high increase in prevalence of about 111 million by 2040. The …

Corneal transplantation is the only treatment for corneal endothelial blindness. However,
there is an urgent need to find substitutes for corneal endothelium grafts due to the global …

Carbon nanomaterials (CNMs), including carbon quantum dots (CQDs), have found
widespread use in biomedical research due to their low toxicity, chemical tunability, and …

The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …

The topically administered glaucoma medications usually encounter serious precorneal
drug loss and low corneal penetration, leading to a low bioavailability. In addition, due to the …

Drug permeation across the cornea remains a major challenge due to its unique and
complex anatomy and physiology. Static barriers such as the different layers of the cornea …