The 2020 WHO classification: what's new in soft tissue tumor pathology?

ME Kallen, JL Hornick - The American journal of surgical …, 2021 - journals.lww.com
The fifth edition of the World Health Organization Classification of Tumors of Soft Tissue and
Bone was published in early 2020. The revisions reflect a consensus among an …

[HTML][HTML] Epithelioid hemangioendothelioma, an ultra-rare cancer: a consensus paper from the community of experts

S Stacchiotti, AB Miah, AM Frezza, C Messiou… - ESMO open, 2021 - Elsevier
Highlights•This consensus paper provides key recommendations on the management of
epithelioid hemangioendothelioma (EHE).•Recommendations followed a consensus …

Soft tissue special issue: perivascular and vascular tumors of the head and neck

U Flucke, M Karanian, RW Broek, K Thway - Head and Neck Pathology, 2020 - Springer
Perivascular and vascular neoplasms of the head and neck are a rare group of tumors
comprising a spectrum of clinical/biologic and histological features. They are frequently …

A cutaneous epithelioid vascular tumor harboring a TPM3::ALK fusion

K Linos, JC Chang, KJ Busam - Genes, Chromosomes and …, 2024 - Wiley Online Library
Substantial progress has been made in understanding the molecular pathways associated
with vascular tumors over the last two decades. In addition to mutations and copy number …

Congenital Vascular and Lymphatic Diseases

R Jung, CM Trivedi - Circulation Research, 2024 - Am Heart Assoc
Over the past several centuries, the integration of contemporary medical techniques and
innovative technologies, like genetic sequencing, have played a pivotal role in enhancing …

Whole Exome Sequencing Identifies Somatic Variants in an Oral Composite Hemangioendothelioma Characterized by YAP1-MAML2 Fusion

IG Koutlas, WS Oetting, GM Burns… - Head and Neck …, 2022 - Springer
Composite hemangioendothelioma (CHE) is considered a borderline malignant vascular
tumor defined by an admixture of distinct vascular neoplastic components. A 21-year-old …

Gene fusions in vascular tumors and their underlying molecular mechanisms

SLM Ong, K Szuhai, JVMG Bovée - Expert review of molecular …, 2021 - Taylor & Francis
Introduction The group of vascular tumors contains many different entities, and is considered
difficult by pathologists, as they often have overlapping histological characteristics …

Identification of stable housekeeping genes for induced pluripotent stem cells and-derived endothelial cells for drug testing

SLM Ong, HJ Baelde, DGP van IJzendoorn… - Scientific Reports, 2022 - nature.com
There are no validated housekeeping genes in induced pluripotent stem cells (iPSC) and
derived endothelial iPSC (iPSC-EC). Thus a comparison of gene expression levels is less …

Fusion transcriptome profiling defines the monoclonal origin of multifocal epithelioid haemangioma of bone

C Errani, I De Benedictis, A Righi, B Valenti… - …, 2023 - Wiley Online Library
Aims Epithelioid haemangioma (EH) of bone remains a highly controversial entity. Indeed,
the WHO classifies EHs of soft tissues as benign tumours, whereas bone EHs are …

Cutaneous epithelioid haemangiomas show somatic mutations in the mitogen‐activated protein kinase pathway

K Maurus, C Kosnopfel, H Kneitz… - British Journal of …, 2022 - academic.oup.com
Background Epithelioid haemangioma (EH) arising from the skin is a benign vascular
tumour with marked inflammatory cell infiltration, which exhibits a high tendency to persist …