3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives
The pharmacology and toxicology of a broad variety of therapies and chemicals have
significantly improved with the aid of the increasing in vitro models of complex human …
significantly improved with the aid of the increasing in vitro models of complex human …
Generation of human myogenic progenitors from pluripotent stem cells for in vivo regeneration
H Kim, RCR Perlingeiro - Cellular and Molecular Life Sciences, 2022 - Springer
Muscular dystrophy encompasses a large number of heterogeneous genetic disorders
characterized by progressive and devastating muscle wasting. Cell-based replacement …
characterized by progressive and devastating muscle wasting. Cell-based replacement …
Diabetes through a 3D lens: organoid models
A Tsakmaki, P Fonseca Pedro, GA Bewick - Diabetologia, 2020 - Springer
Diabetes is one of the most challenging health concerns facing society. Available drugs treat
the symptoms but there is no cure. This presents an urgent need to better understand human …
the symptoms but there is no cure. This presents an urgent need to better understand human …
Tissue engineering for musculoskeletal regeneration and disease modeling
Z Li, S Xiang, EN Li, MR Fritch, PG Alexander… - Organotypic Models in …, 2021 - Springer
Musculoskeletal injuries and associated conditions are the leading cause of physical
disability worldwide. The concept of tissue engineering has opened up novel approaches to …
disability worldwide. The concept of tissue engineering has opened up novel approaches to …
Vascularized organoid-on-a-chip: design, imaging, and analysis
T Yu, Q Yang, B Peng, Z Gu, D Zhu - Angiogenesis, 2024 - Springer
Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep
layers of organoids and provide a more physiologically relevant system in vitro. Common …
layers of organoids and provide a more physiologically relevant system in vitro. Common …
Stem cell-based and tissue engineering approaches for skeletal muscle repair
Skeletal muscle tissue exhibits significant regeneration capacity upon injury or disease. This
intrinsic regeneration potential is orchestrated by stem cells termed satellite cells, which …
intrinsic regeneration potential is orchestrated by stem cells termed satellite cells, which …
Human induced pluripotent stem cell modeling of neurofibromatosis type 1
SV Schurr, KA Hartigan, DH Gutmann - Current Progress in iPSC Disease …, 2022 - Elsevier
Abstract Neurofibromatosis type 1 (NF1) is a common monogenic disorder caused by
germline mutations in a single copy of the NF1 gene. While NF1 is inherited in an autosomal …
germline mutations in a single copy of the NF1 gene. While NF1 is inherited in an autosomal …