[HTML][HTML] An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

S Bastani, V Vahedian, M Rashidi, A Mir… - Biomedicine & …, 2022 - Elsevier
Crocin, an active ingredient derived from saffron, is one of the herbal components that has
recently been considered by researchers. Crocin has been shown to have many anti …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

Ketamine induces ferroptosis of liver cancer cells by targeting lncRNA PVT1/miR-214-3p/GPX4

GN He, NR Bao, S Wang, M Xi, TH Zhang… - Drug design …, 2021 - Taylor & Francis
Background Liver cancer ranks the top four malignant cancer type worldwide, which needs
effective and safe treatment. Ferroptosis is a novel form of regulated cell death driven by iron …

Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Antioxidants, 2022 - mdpi.com
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …

Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation

Y Abdalla, A Abdalla, AA Hamza, A Amin - Frontiers in Pharmacology, 2022 - frontiersin.org
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …

ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo

D Li, C Song, J Zhang, X Zhao - Toxicology, 2022 - Elsevier
Fluorouracil (5-FU) was a key chemotherapeutic agent in the treatment of different solid
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …

[HTML][HTML] Therapeutic potential of camel milk exosomes against HepaRG cells with potent apoptotic, anti-inflammatory, and anti-angiogenesis effects for colostrum …

AM El-Kattawy, O Algezawy, MY Alfaifi… - Biomedicine & …, 2021 - Elsevier
This study aimed to evaluate and compare the therapeutic effect of camel milk exosomes
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …

Dengzhan Xixin injection derived from a traditional Chinese herb Erigeron breviscapus ameliorates cerebral ischemia/reperfusion injury in rats via modulation of …

L Yang, Y Tao, L Luo, Y Zhang, X Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Dengzhan Xixin injection (DX), a preparation of
extracts from traditional Chinese medicine Erigeron breviscapus (Vaniot) Hand.-Mazz., has …

[HTML][HTML] [6]-Gingerol: a narrative review of its beneficial effect on human health

N Promdam, P Panichayupakaranant - Food Chemistry Advances, 2022 - Elsevier
Ginger rhizome, a common spice that has been traditionally used in various health aspects.
The rhizome contains volatile oil and nonvolatile oil compounds, including oleoresin …

Targeting ROS/NF-κB signaling pathway by the seedless black Vitis vinifera polyphenols in CCl4-intoxicated kidney, lung, brain, and spleen in rats

NH Habashy, AS Kodous, MM Abu-Serie - Scientific reports, 2021 - nature.com
Carbon tetrachloride (CCl4) is an abundant environmental pollutant that can generate free
radicals and induce oxidative stress in different human and animal organs like the kidney …