Inflammation is essential in the initial development and progression of many cardiovascular
diseases involving innate and adaptive immune responses. The role of CD4+ CD25+ …

Viral pathogens often induce strong effector CD4+ T cell responses that are best known for
their ability to help B cell and CD8+ T cell responses. However, recent studies have …

Regulatory T (TReg) cells are essential for maintaining peripheral tolerance, preventing
autoimmune diseases and limiting chronic inflammatory diseases. However, they also limit …

Regulatory T (Treg) cells are a critical sub-population of CD4+ T cells that are essential for
maintaining self tolerance and preventing autoimmunity,, for limiting chronic inflammatory …

Many viruses infect humans and most are controlled satisfactorily by the immune system
with limited damage to host tissues. Some viruses, however, do cause overt damage to the …

Ageing is a complex process that negatively impacts the development of the immune system
and its ability to function. The mechanisms that underlie these age‐related defects are broad …

Summary Uncommitted (naive) murine CD4+ T helper cells (Thp) can be induced to
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …

The dynamics of CD4+ effector T cells (Teff cells) and CD4+ Foxp3+ regulatory T cells (Treg
cells) during diabetes progression in nonobese diabetic mice was investigated to determine …

Background The recent identification of a novel coronavirus, also known as severe acute
respiratory syndrome coronavirus 2, has caused a global outbreak of respiratory illnesses …

Regulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the
dominant control of immunological tolerance and maintenance of immune homeostasis …