Bidirectional communication between cumulus cells and the oocyte: old hands and new players?
Cumulus cell–oocyte communication is an essential feature of mammalian reproduction.
Established mechanisms involve the bidirectional transfer of ions and small molecules …
Established mechanisms involve the bidirectional transfer of ions and small molecules …
Human cumulus cells as biomarkers for embryo and pregnancy outcomes
Single-embryo transfer is becoming increasingly common in in vitro fertilization (IVF)
treatment as a means of reducing multiple pregnancy rates leading to a higher incidence of …
treatment as a means of reducing multiple pregnancy rates leading to a higher incidence of …
Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development
KR Dunning, K Cashman, DL Russell… - Biology of …, 2010 - academic.oup.com
Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …
[HTML][HTML] Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer
KM Gebhardt, DK Feil, KR Dunning, M Lane… - Fertility and sterility, 2011 - Elsevier
Objective To identify the cumulus cell gene expression associated with oocyte
developmental competence, specifically live birth, after single ET (SET) assisted …
developmental competence, specifically live birth, after single ET (SET) assisted …
Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by PPAR agonists
KR Dunning, MR Anastasi, VJ Zhang, DL Russell… - PloS one, 2014 - journals.plos.org
Fatty acid oxidation is an important energy source for the oocyte; however, little is known
about how this metabolic pathway is regulated in cumulus-oocyte complexes. Analysis of …
about how this metabolic pathway is regulated in cumulus-oocyte complexes. Analysis of …
Epigenetic dynamics during preimplantation development
In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …
ADAMTS1 cleavage of versican mediates essential structural remodeling of the ovarian follicle and cumulus-oocyte matrix during ovulation in mice
Remodeling of ovarian follicle extracellular matrix is essential for ovulation and
vascularization of the corpus luteum (CL). Formation of the cumulus matrix around oocytes …
vascularization of the corpus luteum (CL). Formation of the cumulus matrix around oocytes …
Increased Beta-Oxidation and Improved Oocyte Developmental Competence in Response to l-Carnitine During Ovarian In Vitro Follicle Development in Mice
Oocyte developmental competence is acquired throughout folliculogenesis and is
associated with appropriate differentiation and responsiveness to the luteinizing hormone …
associated with appropriate differentiation and responsiveness to the luteinizing hormone …
[HTML][HTML] Transcriptome dynamics and molecular cross-talk between bovine oocyte and its companion cumulus cells
The bi-directional communication between the oocyte and its companion cumulus cells
(CCs) is crucial for development and functions of both cell types. Transcripts that are …
(CCs) is crucial for development and functions of both cell types. Transcripts that are …
Gene expression profile of cumulus cells derived from cumulus–oocyte complexes matured either in vivo or in vitro
Although it is well established that maturation conditions have a clear influence on oocyte
developmental competence, it is not known whether this could be due to downstream effects …
developmental competence, it is not known whether this could be due to downstream effects …