Association mapping in plants in the post-GWAS genomics era
PK Gupta, PL Kulwal, V Jaiswal - Advances in genetics, 2019 - Elsevier
With the availability of DNA-based molecular markers during early 1980s and that of
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …
[HTML][HTML] Genome-wide association study and its applications in the non-model crop Sesamum indicum
M Berhe, K Dossa, J You, PA Mboup, IN Diallo… - BMC Plant …, 2021 - Springer
Background Sesame is a rare example of non-model and minor crop for which numerous
genetic loci and candidate genes underlying features of interest have been disclosed at …
genetic loci and candidate genes underlying features of interest have been disclosed at …
False discovery rate control in genome-wide association studies with population structure
We present a comprehensive statistical framework to analyze data from genome-wide
association studies of polygenic traits, producing interpretable findings while controlling the …
association studies of polygenic traits, producing interpretable findings while controlling the …
[HTML][HTML] Estimation of a significance threshold for genome-wide association studies
AS Kaler, LC Purcell - BMC genomics, 2019 - Springer
Background Selection of an appropriate statistical significance threshold in genome-wide
association studies is critical to differentiate true positives from false positives and false …
association studies is critical to differentiate true positives from false positives and false …
Gene hunting with hidden Markov model knockoffs
Modern scientific studies often require the identification of a subset of explanatory variables.
Several statistical methods have been developed to automate this task, and the framework …
Several statistical methods have been developed to automate this task, and the framework …
Improved prediction of bacterial genotype-phenotype associations using interpretable pangenome-spanning regressions
Discovery of genetic variants underlying bacterial phenotypes and the prediction of
phenotypes such as antibiotic resistance are fundamental tasks in bacterial genomics …
phenotypes such as antibiotic resistance are fundamental tasks in bacterial genomics …
[HTML][HTML] Multi-resolution localization of causal variants across the genome
In the statistical analysis of genome-wide association data, it is challenging to precisely
localize the variants that affect complex traits, due to linkage disequilibrium, and to maximize …
localize the variants that affect complex traits, due to linkage disequilibrium, and to maximize …
A novel multitasking ant colony optimization method for detecting multiorder SNP interactions
S Tuo, C Li, F Liu, YL Zhu, TR Chen, ZY Feng… - Interdisciplinary …, 2022 - Springer
Motivation Linear or nonlinear interactions of multiple single-nucleotide polymorphisms
(SNPs) play an important role in understanding the genetic basis of complex human …
(SNPs) play an important role in understanding the genetic basis of complex human …
[HTML][HTML] A multi-marker association method for genome-wide association studies without the need for population structure correction
All common genome-wide association (GWA) methods rely on population structure
correction, to avoid false genotype-to-phenotype associations. However, population …
correction, to avoid false genotype-to-phenotype associations. However, population …
Group inference in high dimensions with applications to hierarchical testing
Z Guo, C Renaux, P Bühlmann… - Electronic Journal of …, 2021 - projecteuclid.org
High-dimensional group inference is an essential part of statistical methods for analysing
complex data sets, including hierarchical testing, tests of interaction, detection of …
complex data sets, including hierarchical testing, tests of interaction, detection of …