Solid tumours are an enormous cancer burden and a major therapeutic challenge. The
cancer stem cell (CSC) hypothesis provides an attractive cellular mechanism to account for …

The possibility of tuberculous pleuritis should be considered in every patient with an
undiagnosed pleural effusion, for if this diagnosis is not made the patient will recover only to …

Since the 2003 guideline, several clinically relevant studies have been published, allowing
new recommendations regarding image guidance of pleural procedures with clear benefits …

A 70-year-old man with an 80-pack-year history of smoking and a history of congestive heart
failure presents with increasing shortness of breath. He also has aching chest pain on the …

A pleural effusion is an excessive accumulation of fluid in the pleural space. It can pose a
diagnostic dilemma to the treating physician because it may be related to disorders of the …

We retrospectively studied the results from thoracenteses and needle biopsies of the pleura
performed in 414 patients with pleural effusions between 1973 and 1982. The final causes …

Malignant pleural effusions are a common clinical problem in patients with neoplastic
disease. In one post mortem series, malignant effusions were found in 15% of patients who …

• Aspiration should not be performed for bilateral effusions in a clinical setting strongly
suggestive of a pleural transudate, unless there are atypical features or they fail to respond …

When a patient with an undiagnosed pleural effusion is evaluated, the first question to
answer is whether the patient has a transudate or an exudate. This is best done using Light's …

Lung cancer (LC) still represents one of the most common tumours in both women and men.
PET/CT is a whole-body non-invasive imaging procedure that has been increasingly used …