The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer's disease
Alzheimer's disease (AD) is neuropathologically characterized by the intracellular
accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β …
accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β …
The role of gamma oscillations in central nervous system diseases: Mechanism and treatment
A Guan, S Wang, A Huang, C Qiu, Y Li, X Li… - Frontiers in cellular …, 2022 - frontiersin.org
Gamma oscillation is the synchronization with a frequency of 30–90 Hz of neural
oscillations, which are rhythmic electric processes of neuron groups in the brain. The …
oscillations, which are rhythmic electric processes of neuron groups in the brain. The …
Orexin signaling modulates synchronized excitation in the sublaterodorsal tegmental nucleus to stabilize REM sleep
H Feng, SY Wen, QC Qiao, YJ Pang, SY Wang… - Nature …, 2020 - nature.com
The relationship between orexin/hypocretin and rapid eye movement (REM) sleep remains
elusive. Here, we find that a proportion of orexin neurons project to the sublaterodorsal …
elusive. Here, we find that a proportion of orexin neurons project to the sublaterodorsal …
Pedunculopontine nucleus: functional organization and clinical implications
EE Benarroch - Neurology, 2013 - AAN Enterprises
The pedunculopontine tegmental nucleus (PPN) is a neurochemically and functionally
heterogeneous structure that occupies a strategic position in the dorsal tegmentum of the …
heterogeneous structure that occupies a strategic position in the dorsal tegmentum of the …
Altered activity in the central medial thalamus precedes changes in the neocortex during transitions into both sleep and propofol anesthesia
How general anesthetics cause loss of consciousness is unknown. Some evidence points
toward effects on the neocortex causing “top-down” inhibition, whereas other findings …
toward effects on the neocortex causing “top-down” inhibition, whereas other findings …
Noise exposure and cardiovascular health
Noise is considered an environmental stressor adversely affecting well-being and quality of
life, inter-individual communications, and attention and cognitive function and inducing …
life, inter-individual communications, and attention and cognitive function and inducing …
Perturbation of brain oscillations after ischemic stroke: a potential biomarker for post-stroke function and therapy
G Rabiller, JW He, Y Nishijima, A Wong… - International journal of …, 2015 - mdpi.com
Brain waves resonate from the generators of electrical current and propagate across brain
regions with oscillation frequencies ranging from 0.05 to 500 Hz. The commonly observed …
regions with oscillation frequencies ranging from 0.05 to 500 Hz. The commonly observed …
Brainstem volume changes in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID patients
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID patients
have overlapping neurological, autonomic, pain, and post-exertional symptoms. We …
have overlapping neurological, autonomic, pain, and post-exertional symptoms. We …
Nondual awareness: consciousness-as-such as non-representational reflexivity
Z Josipovic - Progress in brain research, 2019 - Elsevier
I introduce arguments toward a non-representational reflexivity theory of consciousness-as-
such to address one of the key issues in the science of consciousness today: lack of …
such to address one of the key issues in the science of consciousness today: lack of …
Brainstem abnormalities in myalgic encephalomyelitis/chronic fatigue syndrome: a scoping review and evaluation of magnetic resonance imaging findings
Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a
multisystem medical condition with heterogeneous symptom expression. Currently, there is …
multisystem medical condition with heterogeneous symptom expression. Currently, there is …