Endometriosis: Etiology, pathobiology, and therapeutic prospects
PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …
Pathogenesis of endometriosis: the origin of pain and subfertility
TM Gruber, S Mechsner - Cells, 2021 - mdpi.com
Endometriosis (EM) and adenomyosis (AM) are common conditions with pain and infertility
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …
The sympathetic nervous response in inflammation
G Pongratz, RH Straub - Arthritis research & therapy, 2014 - Springer
Over the past decades evidence has accumulated clearly demonstrating a pivotal role for
the sympathetic nervous system (SNS) and its neurotransmitters in regulating inflammation …
the sympathetic nervous system (SNS) and its neurotransmitters in regulating inflammation …
Endometriosis-associated macrophages: origin, phenotype, and function
Endometriosis is a complex, heterogeneous, chronic inflammatory condition impacting~ 176
million women worldwide. It is associated with chronic pelvic pain, infertility, and fatigue, and …
million women worldwide. It is associated with chronic pelvic pain, infertility, and fatigue, and …
Research priorities for endometriosis: recommendations from a global consortium of investigators in endometriosis
The 3rd International Consensus Workshop on Research Priorities in Endometriosis was
held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis …
held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis …
Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers
AJ Davenport, I Neagoe, N Bräuer, M Koch… - Scientific Reports, 2021 - nature.com
Abstract ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve
fibers and pathological pain pathways. They are also involved in pathways triggering cough …
fibers and pathological pain pathways. They are also involved in pathways triggering cough …
Autonomic nervous system and inflammation interaction in endometriosis-associated pain
Y Wei, Y Liang, H Lin, Y Dai, S Yao - Journal of neuroinflammation, 2020 - Springer
Endometriosis is a chronic inflammatory disease. Pain is the most common symptom in
endometriosis. Endometriosis-associated pain is caused by inflammation, and is related to …
endometriosis. Endometriosis-associated pain is caused by inflammation, and is related to …
Peripheral changes in endometriosis-associated pain
BACKGROUND Pain remains the cardinal symptom of endometriosis. However, to date, the
underlying mechanisms are still only poorly understood. Increasing evidence points towards …
underlying mechanisms are still only poorly understood. Increasing evidence points towards …
Macrophage and nerve interaction in endometriosis
J Wu, H Xie, S Yao, Y Liang - Journal of neuroinflammation, 2017 - Springer
Dysregulation of the immune system in endometriotic milieus has been considered to play a
pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber …
pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber …