Biofilm Formation in Medically Important Candida Species

Z Malinovská, E Čonková, P Váczi - Journal of Fungi, 2023 - mdpi.com
Worldwide, the number of infections caused by biofilm-forming fungal pathogens is very
high. In human medicine, there is an increasing proportion of immunocompromised patients …

Molecular mechanisms of 5-fluorocytosine resistance in yeasts and filamentous fungi

FZ Delma, AMS Al-Hatmi, RJM Brüggemann… - Journal of Fungi, 2021 - mdpi.com
Effective management and treatment of fungal diseases is hampered by poor diagnosis,
limited options for antifungal therapy, and the emergence of antifungal drug resistance. An …

Community-Scale Wastewater Surveillance of Candida auris during an Ongoing Outbreak in Southern Nevada

C Barber, K Crank, K Papp, GK Innes… - Environmental …, 2023 - ACS Publications
Candida auris is an opportunistic fungal pathogen and an emerging global public health
threat, given its high mortality among infected individuals, antifungal resistance, and …

Candida auris: A Quick Review on Identification, Current Treatments, and Challenges

L Černáková, M Roudbary, S Brás, S Tafaj… - International journal of …, 2021 - mdpi.com
Candida auris is a novel and major fungal pathogen that has triggered several outbreaks in
the last decade. The few drugs available to treat fungal diseases, the fact that this yeast has …

Expert recommendations for prevention and management of Candida auris transmission

AM Aldejohann, M Wiese‐Posselt, P Gastmeier… - Mycoses, 2022 - Wiley Online Library
Candida auris was first described as a yeast pathogen in 2009. Since then, the species has
emerged worldwide. In contrast to most other Candida spp., C. auris frequently exhibits multi …

Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida Species

KM Czajka, K Venkataraman, D Brabant-Kirwan… - Cells, 2023 - mdpi.com
Candidiasis is a highly pervasive infection posing major health risks, especially for
immunocompromised populations. Pathogenic Candida species have evolved intrinsic and …

Recent developments in membrane targeting antifungal agents to mitigate antifungal resistance

D Mehta, V Saini, A Bajaj - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
Fungal infections cause severe and life-threatening complications especially in
immunocompromised individuals. Antifungals targeting cellular machinery and cell …

Inhibitory Effects of the Fungal Pigment Rubiginosin C on Hyphal and Biofilm Formation in Candida albicans and Candida auris

H Zeng, M Stadler, WR Abraham, M Müsken, H Schrey - Journal of Fungi, 2023 - mdpi.com
The two fungal human pathogens, Candida auris and Candida albicans, possess a variety
of virulence mechanisms. Among them are the formation of biofilms to protect yeast against …

[HTML][HTML] Candida auris clinical isolates associated with outbreak in neonatal unit of tertiary academic hospital, South Africa

D Kekana, SD Naicker, L Shuping… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Candida auris was first detected at a university-affiliated hospital in Johannesburg, South
Africa, in 2009. We used whole-genome sequencing to describe the molecular …

The Gordian Knot of C. auris: If You Cannot Cut It, Prevent It

V Rapti, K Iliopoulou, G Poulakou - Pathogens, 2023 - mdpi.com
Since its first description in 2009, Candida auris has, so far, resulted in large hospital
outbreaks worldwide and is considered an emerging global public health threat …