Molecular-level anatomy of SARS-CoV-2 for the battle against the COVID-19 pandemic

M Komiyama - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
COVID-19 is currently spreading all over the world, and causing enormous damage to
health, economies, and daily lives. In order to overcome this pandemic, huge amounts of …

Contribution of Chinese herbal medicine in the treatment of coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis of randomized controlled …

D Jin, J Wang, J Xue, Y Zhao, G Yan, X Li… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) has become a global epidemic, and there is
no specific treatment for anti‐COVID‐19 drugs. However, treatment of COVID‐19 using …

Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CLpro

R Wang, Q Hu, H Wang, G Zhu, M Wang… - International Journal of …, 2021 - Elsevier
After the emergence of the pandemic, repurposed drugs have been considered as a quicker
way of finding potential antiviral agents. SARS-CoV-2 3CL pro is essential for processing the …

Natural flavonoid derivatives have pan-coronavirus antiviral activity

M Mori, D Quaglio, A Calcaterra, F Ghirga, L Sorrentino… - Microorganisms, 2023 - mdpi.com
The SARS-CoV-2 protease (3CLpro) is one of the key targets for the development of
efficacious drugs for COVID-19 treatment due to its essential role in the life cycle of the virus …

[HTML][HTML] Study of baicalin toward COVID-19 treatment: in silico target analysis and in vitro inhibitory effects on SARS-CoV-2 proteases

C Lin, FJ Tsai, YM Hsu, TJ Ho, GK Wang, YJ Chiu… - Biomedicine …, 2021 - karger.com
Negative impacts of COVID-19 on human health and economic and social activities urge
scientists to develop effective treatments. Baicalin is a natural flavonoid, extracted from a …

[HTML][HTML] Analysis of COVID-19 prevention and treatment in Taiwan

YJ Chiu, JH Chiang, CW Fu, MJ Hour, HA Ha… - Biomedicine, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) has been spreading worldwide with a mind-
boggling speed. According to a statement from World Health Organization (WHO), COVID …

Urine Metabolites Enable Fast Detection of COVID-19 Using Mass Spectrometry

AV Moura, DC de Oliveira, AAR Silva, JR da Rosa… - Metabolites, 2022 - mdpi.com
The COVID-19 pandemic boosted the development of diagnostic tests to meet patient needs
and provide accurate, sensitive, and fast disease detection. Despite rapid advancements …

A Mini-Review on the Common Antiviral Drug Targets of Coronavirus

J Wang, Q Zhu, X Xing, D Sun - Microorganisms, 2024 - mdpi.com
Coronaviruses in general are a zoonotic pathogen with significant cross-species
transmission. They are widely distributed in nature and have recently become a major threat …

[HTML][HTML] In silico and in vitro studies of Taiwan Chingguan Yihau (NRICM101) on TNF-α/IL-1β-induced Human Lung Cells

YD Cheng, CC Lu, YM Hsu, FJ Tsai, DT Bau… - BioMedicine, 2022 - ncbi.nlm.nih.gov
COVID-19 pandemic has been a global outbreak of coronavirus (SARS-CoV-2 virus) since
2019. Taiwan Chingguan Yihau (NRICM101) is the first traditional Chinese medicine (TCM) …

Rational discovery of antiviral whey protein-derived small peptides targeting the SARS-CoV-2 main protease

N Gambacorta, L Caputo, L Quintieri, L Monaci… - Biomedicines, 2022 - mdpi.com
In the present work, and for the first time, three whey protein-derived peptides (IAEK, IPAVF,
MHI), endowed with ACE inhibitory activity, were examined for their antiviral activity against …