Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

[HTML][HTML] Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids

CH Kim - Cellular & molecular immunology, 2021 - nature.com
A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …

[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease

K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …

Fucoidan ameliorated dextran sulfate sodium-induced ulcerative colitis by modulating gut microbiota and bile acid metabolism

X Liu, Y Zhang, W Li, B Zhang, J Yin… - Journal of agricultural …, 2022 - ACS Publications
Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of
ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism …

Fuzhuan brick tea polysaccharide improved ulcerative colitis in association with gut microbiota-derived tryptophan metabolism

W Yang, D Ren, Y Zhao, L Liu… - Journal of Agricultural and …, 2021 - ACS Publications
Fuzhuanbrick tea (FBT) has attracted wide attention because of its substantial nutritional
value. This article first studied the protective mechanism of FBT polysaccharide (FBTP) on …

A cross-talk between microbiota-derived short-chain fatty acids and the host mucosal immune system regulates intestinal homeostasis and inflammatory bowel …

P Gonçalves, JR Araújo… - Inflammatory bowel …, 2018 - academic.oup.com
Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential
for proper “education” of the immune system. Intestinal microbial communities are able to …

[HTML][HTML] Female gut and genital tract microbiota-induced crosstalk and differential effects of short-chain fatty acids on immune sequelae

E Amabebe, DOC Anumba - Frontiers in Immunology, 2020 - frontiersin.org
The gut and genital tract microbiota of females represent very complex biological
ecosystems that are in continuous communication with each other. The crosstalk between …

[HTML][HTML] Novel Odoribacter splanchnicus Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects in vitro

K Hiippala, G Barreto, C Burrello… - Frontiers in …, 2020 - frontiersin.org
Odoribacter splanchnicus, belonging to the order Bacteroidales, is a common, short-chain
fatty acid producing member of the human intestinal microbiota. A decreased abundance of …

The role of short-chain fatty acids in health and disease

J Tan, C McKenzie, M Potamitis, AN Thorburn… - Advances in …, 2014 - Elsevier
There is now an abundance of evidence to show that short-chain fatty acids (SCFAs) play an
important role in the maintenance of health and the development of disease. SCFAs are a …

[PDF][PDF] Gut microbiota-derived short-chain fatty acids, T cells, and inflammation

CH Kim, J Park, M Kim - Immune network, 2014 - synapse.koreamed.org
T cells are central players in the regulation of adaptive immunity and immune tolerance. In
the periphery, T cell differentiation for maturation and effector function is regulated by a …