The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …
devastating consequences. While the medical community has gained insight into the …
[HTML][HTML] Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison
C Sharma, M Ganigara, C Galeotti, J Burns… - Nature Reviews …, 2021 - nature.com
Children and adolescents infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …
Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis
Background: Cases of adolescents and young adults developing myocarditis after
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
[HTML][HTML] Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia
COVID-19 is a disease with unique characteristics that include lung thrombosis, frequent
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
Neurologic involvement in children and adolescents hospitalized in the United States for COVID-19 or multisystem inflammatory syndrome
KL LaRovere, BJ Riggs, TY Poussaint… - JAMA …, 2021 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) affects the nervous system in adult
patients. The spectrum of neurologic involvement in children and adolescents is unclear …
patients. The spectrum of neurologic involvement in children and adolescents is unclear …
[HTML][HTML] Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …
to acute respiratory distress syndrome and death. Three highly pathogenic human …
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …
[HTML][HTML] Immunology of SARS-CoV-2 infection in children
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …
[HTML][HTML] Monocytes and Macrophages in COVID-19
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …
pandemic with massive global health and socioeconomic consequences. The disease is …
[HTML][HTML] Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans
Antibody responses to SARS-CoV-2 can be detected in most infected individuals 10–15 d
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …