Receptor tyrosine kinases in PI3K signaling: The therapeutic targets in cancer
W Jiang, M Ji - Seminars in Cancer Biology, 2019 - Elsevier
Abstract The phosphoinositide 3-kinase (PI3K) pathway, one of the most commonly
activated signaling pathways in human cancers, plays a crucial role in the regulation of cell …
activated signaling pathways in human cancers, plays a crucial role in the regulation of cell …
Oligonucleotide aptamers against tyrosine kinase receptors: Prospect for anticancer applications
S Camorani, E Crescenzi, M Fedele… - Biochimica et Biophysica …, 2018 - Elsevier
Transmembrane receptor tyrosine kinases (RTKs) play crucial roles in cancer cell
proliferation, survival, migration and differentiation. Area of intense research is searching for …
proliferation, survival, migration and differentiation. Area of intense research is searching for …
[HTML][HTML] Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer
S Camorani, BS Hill, F Collina, S Gargiulo… - Theranostics, 2018 - ncbi.nlm.nih.gov
While the overall mortality for breast cancer has recently declined, management of triple-
negative breast cancer (TNBC) is still challenging because of its aggressive clinical …
negative breast cancer (TNBC) is still challenging because of its aggressive clinical …
Molecular mechanisms of stem/progenitor cell maintenance in the adrenal cortex
AM Lerario, I Finco, C LaPensee… - Frontiers in …, 2017 - frontiersin.org
The adrenal cortex is characterized by three histologically and functionally distinct zones:
the outermost zona glomerulosa (zG), the intermediate zona fasciculata, and the innermost …
the outermost zona glomerulosa (zG), the intermediate zona fasciculata, and the innermost …
Monoclonal antibody-based therapeutics, targeting the epidermal growth factor receptor family: from herceptin to Pan HER
S Moradi-Kalbolandi, A Hosseinzade… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives Monoclonal antibody-based of cancer therapy has been considered as one of the
most successful therapeutic strategies for both haematologic malignancies and solid …
most successful therapeutic strategies for both haematologic malignancies and solid …