Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

OA is a painful joint disease that predominantly affects the elderly. Pain is the primary
symptom of OA, and it can present as either intermittent or constant. OA pain mechanisms …

To study the characteristics of temporal summation (TS) and conditioned pain modulation
(CPM) in fibromyalgia (FM) patients, we systematically searched Pubmed and EMBASE for …

Objective Central sensitization (CS), a mechanism explaining the persistence of symptoms,
has been the focus of many research projects. Explanations given to patients with chronic …

Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …

Background Clinical examination findings are used in primary care to give an initial
diagnosis to patients with low back pain and related leg symptoms. The purpose of this study …

Abstract Changes in central pain processing have been shown in patients with chronic low-
back pain (cLBP). We used quantitative sensory testing methods to identify differences in …

Background Knee osteoarthritis (OA) is among the most common and disabling persistent
pain conditions, with increasing prevalence and impact around the globe. In the US, the …

Osteoarthritis (OA) is a leading cause of pain and disability worldwide. Despite the existence
of evidence-based treatments and guidelines, substantial gaps remain in the quality of OA …

Chronic postoperative pain after total knee replacement (TKR) in knee osteoarthritis (KOA)
implies clinical challenges. Widespread hyperalgesia, facilitated temporal summation of …