Promising role of defensins peptides as therapeutics to combat against viral infection

SS Solanki, P Singh, P Kashyap, MS Sansi… - Microbial pathogenesis, 2021 - Elsevier
Antimicrobial peptides (AMPs) are ubiquitously present small peptides, which play a critical
function in the innate immune system. The defensin class of AMPs represented an …

Bioinformatic HLA studies in the context of SARS‐CoV‐2 pandemic and review on association of HLA alleles with preexisting medical conditions

M Mobini Kesheh, S Shavandi… - BioMed research …, 2021 - Wiley Online Library
After the announcement of a new coronavirus in China in December 2019, which was then
called SARS‐CoV‐2, this virus changed to a global concern and it was then declared as a …

A web-based platform on coronavirus disease-19 to maintain predicted diagnostic, drug, and vaccine candidates

S Patiyal, D Kaur, H Kaur, N Sharma… - Monoclonal …, 2020 - liebertpub.com
A web-based resource CoronaVIR (https://webs. iiitd. edu. in/raghava/coronavir/) has been
developed to maintain the predicted and existing information on coronavirus severe acute …

Exploring SARS-COV-2 structural proteins to design a multi-epitope vaccine using immunoinformatics approach: An in silico study

S Sanami, M Alizadeh, M Nosrati, KA Dehkordi… - Computers in Biology …, 2021 - Elsevier
In December 2019, a new virus called SARS-CoV-2 was reported in China and quickly
spread to other parts of the world. The development of SARS-COV-2 vaccines has recently …

[HTML][HTML] In silico analysis of mutant epitopes in new SARS-CoV-2 lineages suggest global enhanced CD8+ T cell reactivity and also signs of immune response escape

MAM Pretti, RG Galvani, NM Scherer, AS Farias… - Infection, Genetics and …, 2022 - Elsevier
SARS-CoV-2 variants of concern have emerged since the COVID-19 outburst, notably the
lineages detected in the UK, South Africa, and Brazil. Their increased transmissibility and …

[HTML][HTML] Lessons learned from cutting-edge immunoinformatics on next-generation COVID-19 vaccine research

C Chakraborty, AR Sharma, M Bhattacharya… - International Journal of …, 2021 - Springer
Presently, immunoinformatics and bioinformatics approaches are contributing actively to
COVID-19 vaccine research. The first immunoinformatics-based vaccine construct against …

[HTML][HTML] Characterization of the conserved regions of E1A protein from human adenovirus for reinforcement of cytotoxic T lymphocytes responses to the all …

N Omidi, A Azaran, M Makvandi… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Materials and Methods: Bioinformatics' tools were used to predict, refine and validate the 3D
structure of the construct. Effective binding was predicted by protein-protein docking of the …

[HTML][HTML] Mapping potential vaccine candidates predicted by VaxiJen for different viral pathogens between 2017–2021—a scoping review

Z Salod, O Mahomed - Vaccines, 2022 - mdpi.com
Reverse vaccinology (RV) is a promising alternative to traditional vaccinology. RV focuses
on in silico methods to identify antigens or potential vaccine candidates (PVCs) from a …

Design and evaluation of a multi-epitope vaccine for COVID-19: an in silico approach

M Tourani, S Samavarchi Tehrani… - Health Science …, 2023 - hsm.umsu.ac.ir
Background & Aims: Corona virus disease-19 (COVID-19) is an evolving global disease
which has burst into 2019. SARS-CoV-2 infects human cells through recognition of and …

New SARS-CoV-2 lineages could evade CD8+ T-cells response

MAM Pretti, RG Galvani, AS Farias, M Boroni - BioRxiv, 2021 - biorxiv.org
Abstract Background Many SARS-CoV-2 variants of concern have emerged since the Covid-
19 outburst, notably the lineages detected in the UK, South Africa, and Brazil. Their …