Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Graphene, with its excellent physical, chemical, and mechanical properties, holds
tremendous potential for a wide variety of biomedical applications. As research on graphene …

The advent of antibody-based cancer therapeutics has led to the concomitant rise in the
development of companion diagnostics for these therapies, particularly nuclear imaging …

Since the first use of biocompatible mesoporous silica (mSiO2) nanoparticles as drug
delivery vehicles, in vivo tumor targeted imaging and enhanced anticancer drug delivery has …

Herein we demonstrate that nanographene can be specifically directed to the tumor
neovasculature in vivo through targeting of CD105 (ie, endoglin), a vascular marker for …

A multifunctional unimolecular micelle made of a hyperbranched amphiphilic block
copolymer was designed, synthesized, and characterized for cancer-targeted drug delivery …

Identification of cancer cell–surface biomarkers and advances in antibody engineering have
led to a sharp increase in the development of therapeutic antibodies. These same advances …

The goal of this study was to employ nano-graphene for tumor targeting in an animal tumor
model, and quantitatively evaluate the pharmacokinetics and tumor targeting efficacy …

Zirconium-89 has an ideal half-life for use in antibody-based PET imaging; however, when
used with the chelator DFO, there is an accumulation of radioactivity in the bone, suggesting …