The benefits and risks of testosterone replacement therapy: a review

N Bassil, S Alkaade, JE Morley - Therapeutics and clinical risk …, 2009 - Taylor & Francis
Increased longevity and population aging will increase the number of men with late onset
hypogonadism. It is a common condition, but often underdiagnosed and undertreated. The …

Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment

J Buvat, M Maggi, A Guay… - The journal of sexual …, 2013 - academic.oup.com
ABSTRACT Introduction Testosterone (T) deficiency (TD) may significantly affect sexual
function and multiple organ systems. Aim To provide recommendations and Standard …

Evaluation and management of testosterone deficiency: AUA guideline

JP Mulhall, LW Trost, RE Brannigan, EG Kurtz… - The Journal of …, 2018 - auajournals.org
Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …

[HTML][HTML] Sorafenib in advanced clear-cell renal-cell carcinoma

B Escudier, T Eisen, WM Stadler… - … England Journal of …, 2007 - Mass Medical Soc
Background We conducted a phase 3, randomized, double-blind, placebo-controlled trial of
sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients …

Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial

LS Marks, NA Mazer, E Mostaghel, DL Hess, FJ Dorey… - Jama, 2006 - jamanetwork.com
ContextProstate safety is a primary concern when aging men receive testosterone
replacement therapy (TRT), but little information is available regarding the effects of TRT on …

Endocrine aspects of male sexual dysfunctions

J Buvat, M Maggi, L Gooren, AT Guay… - The journal of sexual …, 2010 - academic.oup.com
Introduction Endocrine disorders may adversely affect men's sexual function. Aim To provide
recommendations based on best evidence for diagnosis and treatment of endocrine-related …

A new era of testosterone and prostate cancer: from physiology to clinical implications

M Khera, D Crawford, A Morales, A Salonia… - European urology, 2014 - Elsevier
Context Decades-old beliefs regarding androgens and prostate cancer (PCa) have
undergone dramatic shifts in light of modern evidence and new theoretical constructs, but …

Testosterone and prostate cancer: an historical perspective on a modern myth

A Morgentaler - European urology, 2006 - Elsevier
OBJECTIVES: To review the historical origins and current evidence for the belief that
testosterone (T) causes prostate cancer (pCA) growth. METHODS: Review of the historical …

Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy

AW Pastuszak, AM Pearlman, WS Lai… - The Journal of …, 2013 - auajournals.org
Purpose: Testosterone replacement therapy in men with prostate cancer is controversial,
with concern that testosterone can stimulate cancer growth. We evaluated the safety and …

Testosterone and prostate cancer: an evidence-based review of pathogenesis and oncologic risk

JE Michaud, KL Billups… - Therapeutic advances in …, 2015 - journals.sagepub.com
Testosterone plays a central role in male development and health. Likewise, androgen
deficiency, or hypogonadism, is associated with a variety of symptoms including decreased …