Amino acid transporters revisited: New views in health and disease

P Kandasamy, G Gyimesi, Y Kanai… - Trends in biochemical …, 2018 - cell.com
Amino acid transporters (AATs) are membrane-bound transport proteins that mediate
transfer of amino acids into and out of cells or cellular organelles. AATs have diverse …

Plant SWEETs: from sugar transport to plant–pathogen interaction and more unexpected physiological roles

R Breia, A Conde, H Badim, AM Fortes… - Plant …, 2021 - academic.oup.com
Abstract Sugars Will Eventually be Exported Transporters (SWEETs) have important roles in
numerous physiological mechanisms where sugar efflux is critical, including phloem …

Phosphorylation of SWEET sucrose transporters regulates plant root: shoot ratio under drought

Q Chen, T Hu, X Li, CP Song, JK Zhu, L Chen, Y Zhao - Nature Plants, 2022 - nature.com
The root: shoot ratio has long been known to be enhanced in plants under drought stress.
Here we discovered that osmotic stress enhances long-distance sucrose transport to …

Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies

H Yan, W Xu, J Xie, Y Gao, L Wu, L Sun, L Feng… - Nature …, 2019 - nature.com
Cadmium (Cd) accumulation in rice grain poses a serious threat to human health. While
several transport systems have been reported, the complexity of rice Cd transport and …

Seed filling in domesticated maize and rice depends on SWEET-mediated hexose transport

D Sosso, D Luo, QB Li, J Sasse, J Yang, G Gendrot… - Nature …, 2015 - nature.com
Carbohydrate import into seeds directly determines seed size and must have been
increased through domestication. However, evidence of the domestication of sugar …

Plant SWEET family of sugar transporters: structure, evolution and biological functions

J Ji, L Yang, Z Fang, Y Zhang, M Zhuang, H Lv, Y Wang - Biomolecules, 2022 - mdpi.com
The SWEET (sugars will eventually be exported transporter) family was identified as a new
class of sugar transporters that function as bidirectional uniporters/facilitators and facilitate …

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters

D Deng, N Yan - Protein Science, 2016 - Wiley Online Library
Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …

Simultaneous changes in seed size, oil content and protein content driven by selection of SWEET homologues during soybean domestication

S Wang, S Liu, J Wang, K Yokosho… - National Science …, 2020 - academic.oup.com
Soybean accounts for more than half of the global production of oilseed and more than a
quarter of the protein used globally for human food and animal feed. Soybean domestication …

Plasma membrane-localized SlSWEET7a and SlSWEET14 regulate sugar transport and storage in tomato fruits

X Zhang, C Feng, M Wang, T Li, X Liu… - Horticulture …, 2021 - academic.oup.com
Sugars, especially glucose and fructose, contribute to the taste and quality of tomato fruits.
These compounds are translocated from the leaves to the fruits and then unloaded into the …

Transporter SlSWEET15 unloads sucrose from phloem and seed coat for fruit and seed development in tomato

HY Ko, LH Ho, HE Neuhaus, WJ Guo - Plant Physiology, 2021 - academic.oup.com
Tomato (Solanum lycopersium), an important fruit crop worldwide, requires efficient sugar
allocation for fruit development. However, molecular mechanisms for sugar import to fruits …