Mitochondria are the main source of reactive oxygen species (ROS) in cells. Early studies
have shown that mitochondrial reactive oxygen species (mROS) are related to the …

Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as
cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term …

Aging is the progressive loss of organ and tissue function over time. Growing older is
positively linked to cognitive and biological degeneration such as physical frailty …

Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …

Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases,
inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Clinical and epidemiological studies demonstrate that short-and long-term exposure to air
pollution increases mortality due to respiratory and cardiovascular diseases. Given the …

Aging is a complex phenomenon characterized by the progressive loss of tissue and organ
function. The oxidative-stress theory of aging postulates that age-associated functional …

Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

Numerous abiotic stresses trigger the overproduction of reactive oxygen species (ROS) that
are highly toxic and reactive. These ROS are known to cause damage to carbohydrates …