Since a 2014 meta-analysis, several randomized controlled trials (RCTs) evaluating the
effect of vitamin E intake on glycemic indices and insulin resistance in adults with diabetes …

Oxidative stress is generated by the imbalance between reactive oxygen species (ROS)
formation and antioxidant scavenger system's activity. Increased ROS, such as superoxide …

Vitamin E is one of the most popular fat-soluble vitamins in pathological research and has
been under scrutiny since the 1980s as a vital dietary component of food. The antioxidant …

Oxidative stress and chronic inflammation play an important role in the pathogenesis of
atherosclerosis. Atherosclerosis develops as the first step of vascular endothelial …

BACKGROUND Type 2 diabetes mellitus (T2DM) is a metabolic disease of impaired glucose
utilization. Imbalance in generation and elimination of free radicals generate oxidative stress …

Chronic metabolic diseases arise from changes in metabolic fluxes through biomolecular
pathways and gene networks accumulated over the lifetime of an individual. While clinical …

We have developed a digital twin-based CKD identification and prediction model that
leverages generalized metabolic fluxes (GMF) for patients with Type 2 Diabetes Mellitus …

Atherosclerotic cardiovascular disease (CVD) is the major cause of morbidity and mortality
in individuals with diabetes mellitus (DM). Preclinical models have suggested that excessive …

Nutraceuticals have gained increasing interest, prompting the need to investigate plant
extracts for their beneficial properties and potential side effects. This study aimed to assess …

Background: Vitamin E, an essential micronutrient with antioxidant potential, can
dramatically reduce the cardiovascular risk in individuals with haptoglobin (Hp) 2‐2 …