Biosynthesis and Regulatory Mechanisms of Bioactive Compounds in Salvia miltiorrhiza, a Model System for Medicinal Plant Biology

S Lu - Critical Reviews in Plant Sciences, 2021 - Taylor & Francis
Salvia miltiorrhiza is one of the most well known species in the genus Salvia of the
Lamiaceae with great economic, academic and medicinal value. It was recorded as a …

Tanshinone-IIA mediated neuroprotection by modulating neuronal pathways

K Sherawat, S Mehan - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
The progression of neurological diseases is mainly attributed to oxidative stress, apoptosis,
inflammation, and trauma, making them a primary public concern. Since no drugs can stop …

Molecular mechanism of tanshinone against prostate cancer

W Li, T Huang, S Xu, B Che, Y Yu, W Zhang, K Tang - Molecules, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …

A highly effective turn-on tanshinone IIA-based fluorescent probe for rapid and sensitive detection of ClO− and its application in environmental analysis and …

LL Chen, ZL Wang, L Sun, XB Sun, W Gu - Journal of Photochemistry and …, 2023 - Elsevier
Hypochlorite (ClO−) is an important reactive oxygen species, which is closely related to
many physiological processes and diseases, and plays a crucial role in the innate immune …

Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases

Xue-Zhang, CY Li, GH Zhu, LL Song… - Journal of Agricultural …, 2024 - ACS Publications
Gut microbial bile salt hydrolases (gmBSHs), an important class of bacteria-produced
cysteine hydrolases, play a crucial role in bile acid metabolism. Modulating the total gmBSH …

丹参酮Ⅰ 在肝缺血再灌注损伤小鼠模型中的保护作用.

易小康, 杜毅超, 钱保林, 黄治伟… - Journal of Clinical …, 2021 - search.ebscohost.com
易小康a,b,杜毅超a,b,钱保林b,黄治伟b,李秋b,付文广a,b,温剑a,b Page 1 !MN)+! 丹参酮I在肝缺血
再灌注损伤小鼠模型中的保护作用 易小康a,b,杜毅超a,b,钱保林b,黄治伟b,李秋b,付文广a,b,温剑 …

Diterpenoid tanshinone attenuates the metastasis of non-small-cell lung cancer (NSCLC) cells by inhibiting the Cavin-1-mediated ERK/Smad2 signaling pathway

L Wang, G Jiang, X Li - Anti-Cancer Agents in Medicinal …, 2023 - ingentaconnect.com
Background: Non-small cell lung cancer (NSCLC) is a common malignant cancer with high
incidence and mortality. In recent decade, despite the progress in the treatment and …

Electrochemical oxidative site-selective direct C–H activation of tanshinone IIA

J Zhang, S Han, S Lu, M Li, Z Gao, L Zheng… - Organic & …, 2024 - pubs.rsc.org
Natural products play a pivotal role in the advancement of state-of-the-art pharmaceuticals.
To augment their therapeutic efficacy, structural modifications of these compounds are …

Comparative profiling of the absorbed compounds and metabolites, and pharmacokinetic studies of Danshen-Chuanxiong herb pair in rat plasma and brain using …

JX Guo, Y Yang, YJ Zhao, J Wang, H Liu, L Xu… - … of Pharmaceutical and …, 2025 - Elsevier
Abstract Danshen-Chuanxiong (DS-CX) was a classic herb pair commonly used to treat
ischemic stroke. Nevertheless, the metabolic conversion and pharmacokinetic behavior of …

[HTML][HTML] Tanshinones from Salvia miltiorrhiza inhibit Mycobacterium tuberculosis via disruption of the cell envelope surface and oxidative stress

E Sieniawska, R Sawicki, AS Marchev… - Food and Chemical …, 2021 - Elsevier
The unique structure of Mycobacterium tuberculosis cell envelope provides impermeable
barrier against environmental stimuli. In the situation that this barrier is disturbed …