Advances in the diagnosis, evaluation, and management of leptomeningeal disease

U Sener, P Kumthekar, A Boire - Neuro-Oncology Advances, 2021 - academic.oup.com
Leptomeningeal metastasis (LM) is a devastating complication of cancer with variable
clinical presentation and limited benefit from existing treatment options. In this review, we …

[HTML][HTML] Best practices for the use of intracerebroventricular drug delivery devices

I Slavc, JL Cohen-Pfeffer, S Gururangan… - Molecular Genetics and …, 2018 - Elsevier
Abstract For decades, intracerebroventricular (ICV), or intraventricular, devices have been
used in the treatment of a broad range of pediatric and adult central nervous system (CNS) …

[HTML][HTML] Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

CM Ferguson, BMDC Godinho, JF Alterman, AH Coles… - JCI insight, 2021 - ncbi.nlm.nih.gov
Abstract siRNAs comprise a class of drugs that can be programmed to silence any target
gene. Chemical engineering efforts resulted in development of divalent siRNAs (di-siRNAs) …

Operative complications with and without image guidance: A systematic review and meta-analysis of the Ommaya reservoir literature

JC Lau, SE Kosteniuk, T Walker, A Iansavichene… - World Neurosurgery, 2019 - Elsevier
Background The use of image guidance (IG) in neurosurgery is ubiquitous, even though
evidence from patient outcome data has remained limited to smaller, mostly observational …

[HTML][HTML] Ommaya reservoir

A Zubair, O De Jesus - 2020 - europepmc.org
Objectives: Identify the anatomical structures, indications, and contraindications of Ommaya
reservoir insertion. Describe the equipment, personnel, preparation, and technique in …

脑脊液途径给药神经修复治疗的中国专家共识(2022 版).

陈琳, 张志强 - … of Tissue Engineering Research/Zhongguo zu …, 2023 - search.ebscohost.com
摘要背景: 目前神经修复药物的开发和给药方式仍然具有挑战性, 加上神经系统受到血脑屏障和
血脑脊液屏障的高度保护, 限制了大多数药物的临床治疗效果. 通过脑脊液途径直接给药至神经 …

Complications of intracerebroventricular chemotherapy via subgaleal reservoir in primary central nervous system lymphoma: A single‐institution experience on 1247 …

S Anton, M Margold, T Kowalski, D Miller… - Hematological …, 2021 - Wiley Online Library
The implantation of a subgaleal reservoir intracerebroventricular (ICV port) in order to apply
ICV chemotherapy in patients with leptomeningeal cancer may be complicated by …

Intraventricular administration of antibiotics by ommaya reservoir for patients with multidrug-resistant Acinetobacter baumannii central nervous system infection

Y Chen, L Liu, M Zhu - British Journal of Neurosurgery, 2021 - Taylor & Francis
Aim To investigate whether the Ommaya reservoir can be used to treat multiple drug-
resistant Acinetobacter baumannii (MDR-AB) infections in the central nervous system (CNS) …

[PDF][PDF] Ommaya reservoir related complications: a single center experience and review of current literature

A Ali, RC Bosse, BP Doonan, P Narayan… - Int J Clin Oncol …, 2019 - researchgate.net
First introduced in 1963, ommaya reservoirs (OmRs) are indwelling intraventricular catheters
used for decompression of hydrocephalus, antibiotics, and chemotherapy delivery. They are …

Evolution of the retinal function by flash-ERG in one child suffering from neuronal ceroid lipofuscinosis CLN2 treated with cerliponase alpha: case report

F Rigaudière, H Nasser, S Pichard-Oumlil… - Documenta …, 2021 - Springer
Introduction Neuronal ceroid lipofuscinoses (CLN) are neurodegenerative disorders among
the most frequent, inherited as an autosomal recessive trait. Affected patients can present …