Selenium (Se) is a naturally occurring metalloid element essential to human and animal
health in trace amounts but it is harmful in excess. Se plays a substantial role in the …

Thyroid hormone (TH) is required for normal development as well as regulating metabolism
in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially …

Inflammation and oxidative stress (OS) are closely related processes, as well exemplified in
obesity and cardiovascular diseases. OS is also related to hormonal derangement in a …

Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …

Tanycytes, glial-like cells that line the third ventricle, are emerging as components of the
hypothalamic networks that control body weight and energy balance. They contact the …

Estrogen affects proliferation and migration of different skin components, thus influencing
wound healing processes. The human keratinocyte cell line NCTC 2544 has been used to …

The human selenoprotein family contains 25 members that share the common feature of
containing the amino acid, selenocysteine (Sec). Seven selenoproteins are localized to the …

Summary Triiodothyronine (T3), the active form of thyroid hormone is produced
predominantly outside the thyroid parenchyma secondary to peripheral tissue deiodination …

This paper provides the reader with an overview of our current knowledge of hypothalamic‐
pituitary‐thyroid feedback from a cybernetic standpoint. Over the past decades we have …

BACKGROUND: Thyroid hormone signaling is critical for development, growth and
metabolic control in vertebrates. Although serum concentration of thyroid hormone is …