Basic human functions such as breathing and digestion require mechanical stretching of
cells and tissues. However, when it comes to laboratory experiments, the mechanical …

Our understanding of free-living bacterial models like Escherichia coli far outpaces that of
obligate intracellular bacteria, which cannot be cultured axenically. All obligate intracellular …

Cells living in geometrically confined microenvironments are ubiquitous in various
physiological processes, eg, wound closure. However, it remains unclear whether and how …

Cell competition refers to the mechanism whereby less fit cells (“losers”) are sensed and
eliminated by more fit neighboring cells (“winners”) and arises during many processes …

Mechanical signals are crucial in regulating the response of cells in a monolayer to both
physiological and pathological stressors, including intracellular bacterial infections. In …

The dissemination of protozoan and metazoan parasites through host tissues is hindered by
cellular barriers, dense extracellular matrices, and fluid forces in the bloodstream. To …

Intracellular bacterial infections alter the normal functionality of human host cells and
tissues. Infection can also modify the mechanical properties of host cells, altering the …

Borrelia burgdorferi (Bb), a vector-borne bacterial pathogen and the causative agent of
Lyme disease, can spread to distant tissues in the human host by traveling in and through …

Cell motility and biomechanics are critical in various (patho) physiological processes,
including the regulation of vascular barrier integrity, which can be subverted by bacterial …

Introduction. The lung environment is defined by unique biological boundary conditions,
including complex alveolar geometry, extracellular matrix composition and mechanical …