[HTML][HTML] Selective autophagy of intracellular organelles: recent research advances
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …
that degrades over-abundant or damaged organelles, large protein aggregates and …
The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
[HTML][HTML] L-carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine
MR McCann, MV George De la Rosa, GR Rosania… - Metabolites, 2021 - mdpi.com
Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …
movement. Modern advances in the field of metabolomics afford the opportunity to readily …
[HTML][HTML] Crosstalk between mammalian autophagy and the ubiquitin-proteasome system
NM Kocaturk, D Gozuacik - Frontiers in cell and developmental …, 2018 - frontiersin.org
Autophagy and the ubiquitin–proteasome system (UPS) are the two major intracellular
quality control and recycling mechanisms that are responsible for cellular homeostasis in …
quality control and recycling mechanisms that are responsible for cellular homeostasis in …
[HTML][HTML] Mechanisms mediating the regulation of peroxisomal fatty acid beta-oxidation by PPARα
M Tahri-Joutey, P Andreoletti, S Surapureddi… - International journal of …, 2021 - mdpi.com
In mammalian cells, two cellular organelles, mitochondria and peroxisomes, share the ability
to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation …
to degrade fatty acid chains. Although each organelle harbors its own fatty acid β-oxidation …
Photochromic fluorescent probe strategy for the super-resolution imaging of biologically important biomarkers
X Chai, HH Han, AC Sedgwick, N Li… - Journal of the …, 2020 - ACS Publications
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG,
that was designed to prebind to human serum albumin (HSA) to form the probe/protein …
that was designed to prebind to human serum albumin (HSA) to form the probe/protein …
[HTML][HTML] Dietary restriction and AMPK increase lifespan via mitochondrial network and peroxisome remodeling
Mitochondrial network remodeling between fused and fragmented states facilitates
mitophagy, interaction with other organelles, and metabolic flexibility. Aging is associated …
mitophagy, interaction with other organelles, and metabolic flexibility. Aging is associated …
Comparison of tofogliflozin and glimepiride effects on nonalcoholic fatty liver disease in participants with type 2 diabetes: a randomized, 48-week, open-label, active …
Y Takeshita, M Honda, K Harada, Y Kita… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Nonalcoholic fatty liver disease (NAFLD) is a liver phenotype of type 2 diabetes
and obesity. Currently, the efficacy of sodium–glucose cotransporter 2 (SGLT2) inhibitors …
and obesity. Currently, the efficacy of sodium–glucose cotransporter 2 (SGLT2) inhibitors …
[HTML][HTML] Ubiquitin-mediated regulation of autophagy
RH Chen, YH Chen, TY Huang - Journal of Biomedical Science, 2019 - Springer
Autophagy is a major degradation pathway that utilizes lysosome hydrolases to degrade
cellular constituents and is often induced under cellular stress conditions to restore cell …
cellular constituents and is often induced under cellular stress conditions to restore cell …
[HTML][HTML] The peroxisome-mitochondria connection: how and why?
M Fransen, C Lismont, P Walton - International journal of molecular …, 2017 - mdpi.com
Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …
and reactive oxygen species metabolism. In mammals, these organelles have also been …