The rapid increase in the number of diabetic patients globally and exploration of alternate
insulin delivery methods such as inhalation or oral route that rely on higher doses, is bound …

Escherichia coli is the most preferred microorganism to express heterologous proteins for
therapeutic use, as around 30% of the approved therapeutic proteins are currently being …

Carbon dioxide (CO2) is an important carbon feedstock for a future green economy. This
requires the development of efficient strategies for its conversion into multicarbon …

Historically, room-temperature structure determination was succeeded by cryo-
crystallography to mitigate radiation damage. Here, we demonstrate that serial millisecond …

Cold-active enzymes constitute an attractive resource for biotechnological applications.
Their high catalytic activity at temperatures below 25° C makes them excellent biocatalysts …

Most of the hosts used to produce the 151 recombinant pharmaceuticals so far approved for
human use by the Food and Drug Administration (FDA) and/or by the European Medicines …

An increasing focus on environmental sustainability has led to an ongoing global effort to
better understand and engineer platform organisms that economically convert CO 2 and …

Different species of microorganisms including yeasts, filamentous fungi and bacteria have
been used in the past 25 years for the controlled production of foreign proteins of scientific …

Protein expression in Escherichia coli represents the most facile approach for the
preparation of non-glycosylated proteins for analytical and preparative purposes. So far, the …

Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …