[HTML][HTML] Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials: Based on the mechanisms of occurrence and development of …

J Liao, X Li, Y Fan - Bioactive Materials, 2023 - Elsevier
Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …

Establishments and evaluations of post‐operative adhesion animal models

Y Wang, W Zhai, L Yang, S Cheng… - Advanced …, 2023 - Wiley Online Library
After abdominopelvic surgery, there are 90–93% of patients who develop postoperative
adhesions. Post‐operative adhesions can occur after various surgical procedures, which not …

An ultrasoft self‐fused supramolecular polymer hydrogel for completely preventing postoperative tissue adhesion

J Yu, K Wang, C Fan, X Zhao, J Gao, W Jing… - Advanced …, 2021 - Wiley Online Library
The intermolecular H‐bonding density heavily influences the gelation and rheological
behavior of hydrogen‐bonded supramolecular polymer hydrogels, thus offering a delicate …

[HTML][HTML] Post-operative adhesions: a comprehensive review of mechanisms

A Fatehi Hassanabad, AN Zarzycki, K Jeon, JF Deniset… - Biomedicines, 2021 - mdpi.com
Post-surgical adhesions are common in almost all surgical areas and are associated with
significant rates of morbidity, mortality, and increased healthcare costs, especially when a …

[HTML][HTML] Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

PA Louwe, L Badiola Gomez, H Webster… - Nature …, 2021 - nature.com
Inflammation generally leads to recruitment of monocyte-derived macrophages. What
regulates the fate of these cells and to what extent they can assume the identity and function …

[HTML][HTML] The multifaceted role of plasminogen in inflammation

B Heissig, Y Salama, S Takahashi, T Osada, K Hattori - Cellular signalling, 2020 - Elsevier
A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the
execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted …

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

J Chen, X Tang, Z Wang, A Perez, B Yao… - Bioengineering & …, 2023 - Wiley Online Library
Postsurgical adhesions are a common complication of surgical procedures that can lead to
postoperative pain, bowel obstruction, infertility, as well as complications with future …

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

CC Bain, DA Gibson, NJ Steers, K Boufea… - Science …, 2020 - science.org
Macrophages reside in the body cavities where they maintain serosal homeostasis and
provide immune surveillance. Peritoneal macrophages are implicated in the etiology of …

[HTML][HTML] Cell barrier function of resident peritoneal macrophages in post-operative adhesions

T Ito, Y Shintani, L Fields, M Shiraishi… - Nature …, 2021 - nature.com
Post-operative adhesions are a leading cause of abdominal surgery-associated morbidity.
Exposed fibrin clots on the damaged peritoneum, in which the mesothelial barrier is …

Postoperative peritoneal adhesion: an update on physiopathology and novel traditional herbal and modern medical therapeutics

S Soltany - Naunyn-Schmiedeberg's Archives of Pharmacology, 2021 - Springer
Postoperative peritoneal adhesion (PPA) is a serious clinical condition that affects the high
percentage of patients after abdominal surgery. In this review, we have tried to focus on …